Date published: 2026-4-30

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Tegaserod (CAS 145158-71-0)

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Alternate Names:
Zelmac; Zelnorm
Application:
Tegaserod is a serotonin 4 inhibitor
CAS Number:
145158-71-0
Molecular Weight:
301.39
Molecular Formula:
C16H23N5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tegaserod (CAS 145158-71-0) References

  1. Tegaserod: a novel, selective 5-HT4 receptor partial agonist for irritable bowel syndrome.  |  Beglinger, C. 2002. Int J Clin Pract. 56: 47-51. PMID: 11831835
  2. Clinical pharmacokinetics of tegaserod, a serotonin 5-HT(4) receptor partial agonist with promotile activity.  |  Appel-Dingemanse, S. 2002. Clin Pharmacokinet. 41: 1021-42. PMID: 12403641
  3. [Tegaserod inhibits noxious rectal distention induced response and spinal nNOS expression in rats with visceral hypersensitivity].  |  Jiao, HM. and Xie, PY. 2004. Beijing Da Xue Xue Bao Yi Xue Ban. 36: 394-8. PMID: 15303133
  4. Tegaserod inhibits noxious rectal distention induced responses and limbic system c-Fos expression in rats with visceral hypersensitivity.  |  Jiao, HM. and Xie, PY. 2004. World J Gastroenterol. 10: 2836-41. PMID: 15334681
  5. Tegaserod (HTF 919) stimulates gut motility in normal horses.  |  Lippold, BS., et al. 2004. Equine Vet J. 36: 622-7. PMID: 15581328
  6. Tegaserod: a serotonin 5-HT4 receptor agonist for treatment of constipation-predominant irritable bowel syndrome.  |  Cole, P. and Rabasseda, X. 2004. Drugs Today (Barc). 40: 1013-30. PMID: 15645012
  7. Antinociceptive property of tegaserod in a rat model of chronic visceral hypersensitivity.  |  Liang, LX., et al. 2005. Chin J Dig Dis. 6: 21-5. PMID: 15667554
  8. Alosetron, cilansetron and tegaserod modify mesenteric but not colonic blood flow in rats.  |  Painsipp, E., et al. 2009. Br J Pharmacol. 158: 1210-26. PMID: 19785647
  9. Tegaserod, a small compound mimetic of polysialic acid, promotes functional recovery after spinal cord injury in mice.  |  Pan, HC., et al. 2014. Neuroscience. 277: 356-66. PMID: 25014876
  10. Effect of the 5-HT4 receptor agonist tegaserod on the expression of GRK2 and GRK6 in the rat gastrointestinal tract.  |  Nedi, T., et al. 2018. BMC Res Notes. 11: 362. PMID: 29884229
  11. Tegaserod Maleate Inhibits Breast Cancer Progression and Enhances the Sensitivity of Immunotherapy.  |  Li, X., et al. 2022. J Oncol. 2022: 5320421. PMID: 35154317
  12. Tegaserod Maleate Suppresses the Growth of Gastric Cancer In Vivo and In Vitro by Targeting MEK1/2.  |  Wang, Z., et al. 2022. Cancers (Basel). 14: PMID: 35892850
  13. Tegaserod maleate exhibits antileukemic activity by targeting TRPM8.  |  Xie, X., et al. 2022. Biomed Pharmacother. 154: 113566. PMID: 35994820

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tegaserod, 100 mg

sc-338608
100 mg
$1248.00