Molecular structure of TDCPP, CAS Number: 13674-87-8
TDCPP (CAS 13674-87-8)
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Alternate Names:
Tris(1,3-dichloro-2-propyl) phosphate
Application:
TDCPP is a flame retardant
CAS Number:
13674-87-8
Purity:
≥90%
Molecular Weight:
430.90
Molecular Formula:
C9H15Cl6O4P
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
TDCPP functions as a flame retardant in various experimental applications. It acts by interfering with the combustion process, reducing the flammability of materials to which it is applied. At the molecular level, TDCPP interacts with the material′s surface, forming a protective layer that inhibits the spread of fire. Its mode of action involves disrupting chemical reactions that occur during combustion, thereby slowing down or preventing the ignition and propagation of flames. In experimental applications, TDCPP is utilized for its ability to enhance the fire resistance of materials, making it a component in studies focused on improving the safety and durability of various products.
TDCPP (CAS 13674-87-8) References
- Effects of organophosphorus flame retardant TDCPP on normal human corneal epithelial cells: Implications for human health. | Xiang, P., et al. 2017. Environ Pollut. 230: 22-30. PMID: 28641197
- TDCPP protects cardiomyocytes from hypoxia-reoxygenation injury induced apoptosis through mitigating calcium overload and promotion GSK-3β phosphorylation. | He, X., et al. 2018. Regul Toxicol Pharmacol. 92: 39-45. PMID: 29129621
- TDCPP protects cardiomyocytes from H2O2-induced injuries via activating PI3K/Akt/GSK3β signaling pathway. | Zhang, W., et al. 2019. Mol Cell Biochem. 453: 53-64. PMID: 30173372
- Metabolomics reveals that tris(1,3-dichloro-2-propyl)phosphate (TDCPP) causes disruption of membrane lipids in microalga Scenedesmus obliquus. | Wang, L., et al. 2020. Sci Total Environ. 708: 134498. PMID: 31796289
- Neonatal exposure to organophosphorus flame retardant TDCPP elicits neurotoxicity in mouse hippocampus via microglia-mediated inflammation in vivo and in vitro. | Zhong, X., et al. 2020. Arch Toxicol. 94: 541-552. PMID: 31894355
- Toxic effect and mechanism of tris (1,3-dichloro-2-propyl)phosphate (TDCPP) on the marine alga Phaeodactylum tricornutum. | Liu, Q., et al. 2020. Chemosphere. 252: 126467. PMID: 32222518
- Organophosphorus flame retardant TDCPP-induced cytotoxicity and associated mechanisms in normal human skin keratinocytes. | Cui, D., et al. 2020. Sci Total Environ. 726: 138526. PMID: 32304943
- TDCPP mimics thyroid hormones associated with the activation of integrin αvβ3 and ERK1/2. | Li, J., et al. 2020. Chemosphere. 256: 127066. PMID: 32434091
- The toxicity effects and mechanisms of tris(1,3-dichloro-2-propyl) phosphate (TDCPP) and its ecological risk assessment for the protection of freshwater organisms. | Liu, D., et al. 2020. Environ Pollut. 264: 114788. PMID: 32559856
- Time-course effects of Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) on Chlorella pyrenoidosa: Growth inhibition and adaptability mechanisms. | Zhang, X., et al. 2021. J Hazard Mater. 402: 123784. PMID: 33254794
- Organophosphorus Flame Retardant TDCPP Displays Genotoxic and Carcinogenic Risks in Human Liver Cells. | Saquib, Q., et al. 2022. Cells. 11: PMID: 35053312
- Effects of long-term exposure to TDCPP in zebrafish (Danio rerio) - Alternations of hormone balance and gene transcriptions along hypothalamus-pituitary axes. | Liu, X., et al. 2022. Animal Model Exp Med. 5: 239-247. PMID: 35234363
- Organophosphate flame retardant TDCPP: A risk factor for renal cancer? | Zhou, X., et al. 2022. Chemosphere. 305: 135485. PMID: 35764118
- Organophosphorus flame retardant TDCPP induces neurotoxicity via mitophagy-related ferroptosis in vivo and in vitro. | Qian, B., et al. 2022. Chemosphere. 308: 136345. PMID: 36087716
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TDCPP, 100 mg | sc-229356 | 100 mg | $78.00 | |||
TDCPP, 1 g | sc-229356A | 1 g | $148.00 |