Molecular structure of TCS PIM-1 1, CAS Number: 491871-58-0
TCS PIM-1 1 (CAS 491871-58-0)
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Alternate Names:
6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile
Application:
TCS PIM-1 1 is an ATP-competitive Pim-1 kinase inhibitor
CAS Number:
491871-58-0
Purity:
>98%
Molecular Weight:
367.2
Molecular Formula:
C18H11BrN2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
TCS PIM-1 1, is an intriguing heterocyclic compound that has captured the attention of scientific researchers. This compound exhibits a diverse range of applications in vitro studies. Numerous scientific research applications have utilized TCS PIM-1 1. Although the complete mechanism of action for this compound remains elusive, current understanding suggests its role as an agonist at the γ-aminobutyric acid (GABA) receptor.
TCS PIM-1 1 (CAS 491871-58-0) References
- Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach. | Abadi, AH., et al. 2010. Eur J Med Chem. 45: 90-7. PMID: 19836860
- Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics. | Hafner, M., et al. 2017. Sci Data. 4: 170166. PMID: 29112189
- Abemaciclib, A Selective CDK4/6 Inhibitor, Restricts the Growth of Pediatric Ependymomas. | Liang, ML., et al. 2020. Cancers (Basel). 12: PMID: 33271970
- PIM1-Induced Cytoplasmic Expression of RBMY Mediates Hepatocellular Carcinoma Metastasis. | Chua, HH., et al. 2023. Cell Mol Gastroenterol Hepatol. 15: 121-152. PMID: 36191855
- Inhibition of IκB Kinase Is a Potential Therapeutic Strategy to Circumvent Resistance to Epidermal Growth Factor Receptor Inhibition in Triple-Negative Breast Cancer Cells. | Yi, YW., et al. 2022. Cancers (Basel). 14: PMID: 36358633
Inhibitor of:
Pim-1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TCS PIM-1 1, 10 mg | sc-204330 | 10 mg | $179.00 | |||
TCS PIM-1 1, 50 mg | sc-204330A | 50 mg | $714.00 |