Date published: 2025-10-2

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TCPP (CAS 13674-84-5)

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Alternate Names:
Tris(1-chloro-2-propyl) phosphate
Application:
TCPP is a mixture of isomers
CAS Number:
13674-84-5
Molecular Weight:
327.57
Molecular Formula:
C9H18Cl3O4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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TCPP is a synthetic porphyrin compound that is widely used in the field of materials science. Its four carboxyphenyl groups allow for versatile functionalization, which is particularly valuable in the design and synthesis of metal-organic frameworks (MOFs). Researchers focus on TCPP′s ability to coordinate with a variety of metal ions, forming stable, porous structures that can be utilized for gas storage, separation, and catalysis studies. The compound′s large conjugated system and inherent porphyrin core are of interest in photophysical and photochemical research, where TCPP is used to investigate light-harvesting properties and energy transfer processes. Additionally, TCPP serves as a building block in the development of organic electronics and optoelectronic devices, due to its potential for light absorption and electron transport.


TCPP (CAS 13674-84-5) References

  1. Isomers of tris(chloropropyl) phosphate (TCPP) in technical mixtures and environmental samples.  |  Truong, JW., et al. 2017. Anal Bioanal Chem. 409: 6989-6997. PMID: 29147747
  2. Improved Performance of Polysulfone Ultrafiltration Membrane Using TCPP by Post-Modification Method.  |  Jia, Y., et al. 2020. Membranes (Basel). 10: PMID: 32272800
  3. Removal of tri-(2-chloroisopropyl) phosphate (TCPP) by three types of constructed wetlands.  |  Qin, P., et al. 2020. Sci Total Environ. 749: 141668. PMID: 32836133
  4. Proteomic analysis revealed gender-specific responses of mussels (Mytilus galloprovincialis) to trichloropropyl phosphate (TCPP) exposure.  |  Zhong, M., et al. 2020. Environ Pollut. 267: 115537. PMID: 32892020
  5. Fe-TCPP@CS nanoparticles as photodynamic and photothermal agents for efficient antimicrobial therapy.  |  Zhang, Y., et al. 2020. Biomater Sci. 8: 6526-6532. PMID: 33103167
  6. Identification of a novel mechanism for meso-tetra (4-carboxyphenyl) porphyrin (TCPP) uptake in cancer cells.  |  Elzi, DJ., et al. 2021. FASEB J. 35: e21427. PMID: 33629776
  7. TCPP-Isoliensinine Nanoparticles for Mild-Temperature Photothermal Therapy.  |  Zhang, C., et al. 2021. Int J Nanomedicine. 16: 6797-6806. PMID: 34675508
  8. Biocompatible 2D Cu-TCPP Nanosheets Derived from Cu2O Nanocubes as Multifunctional Nanoplatforms for Combined Anticancer Therapy.  |  Gao, L., et al. 2022. ACS Biomater Sci Eng. 8: 1074-1086. PMID: 35129963
  9. Preparation and Characterization of TCPP-CaMMT Nanocompound and Its Composite with Polypropylene.  |  Geng, J., et al. 2022. Nanomaterials (Basel). 12: PMID: 35564137
  10. nTiO2 alleviates the toxic effects of TCPP on mussels by adjusting respiratory metabolism and gut microbiota.  |  Deng, F., et al. 2022. Sci Total Environ. 851: 158176. PMID: 35995159
  11. Organophosphorus Flame Retardant TCPP Induces Cellular Senescence in Normal Human Skin Keratinocytes: Implication for Skin Aging.  |  Liu, JX., et al. 2022. Int J Mol Sci. 23: PMID: 36430782
  12. Genotoxic and Toxic Effects of The Flame Retardant Tris(Chloropropyl) Phosphate (TCPP) in Human Lymphocytes, Microalgae and Bacteria.  |  Antonopoulou, M., et al. 2022. Toxics. 10: PMID: 36548569
  13. Effects of TCPP and TCEP exposure on human corneal epithelial cells: Oxidative damage, cell cycle arrest, and pyroptosis.  |  Zhang, ZN., et al. 2023. Chemosphere. 331: 138817. PMID: 37127200
  14. TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae.  |  Häse, CC. and Mekalanos, JJ. 1998. Proc Natl Acad Sci U S A. 95: 730-4. PMID: 9435261

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

TCPP, 100 mg

sc-251106
100 mg
$222.00