TCEAL1 Antibody (SS-M5): sc-135577
- TCEAL1 Antibody (SS-M5) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against recombinant TCEAL1 protein of human origin
- recommended for detection of TCEAL1 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for TCEAL1 Antibody (SS-M5). This work is in progress.
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TCEAL1 Antibody (SS-M5) is a mouse monoclonal IgG2a antibody that detects TCEAL1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). TCEAL1, also known as transcription elongation factor A (SII) protein 3, p21, SIIR, or pp21, plays a crucial role in the regulation of transcription by facilitating the release of RNA polymerase II from transcriptional arrest, which is essential for proper gene expression. This 157 amino acid nuclear protein is ubiquitously expressed and is known to interact with various transcriptional regulators, suggesting that TCEAL1 function may be mediated through protein-protein interactions rather than direct DNA binding. Notably, TCEAL1 undergoes phosphorylation at Serine 36 and Serine 37, modifications that are critical for its role in transcriptional repression, highlighting the importance of post-translational modifications in regulating TCEAL1 activity and, consequently, gene expression. TCEAL1 (SS-M5) antibody is an invaluable tool for researchers studying transcriptional regulation and the intricate mechanisms that govern gene expression in human cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TCEAL1 Antibody (SS-M5) | sc-135577 | 100 µg/ml | $339.00 |