Date published: 2025-10-19

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TBPP (CAS 126-72-7)

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Alternate Names:
TDBPP; Tris(2,3-dibromopropyl) phosphate
Application:
TBPP is a carcinogenic manufacturing component
CAS Number:
126-72-7
Molecular Weight:
697.61
Molecular Formula:
C9H15Br6O4P
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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TBPP, or Tris(2,3-dibromopropyl) phosphate, is a chemical compound primarily studied for its role in flame retardancy mechanisms at the molecular level. In research settings, TBPP has been extensively used to understand the chemistry of halogenated fire retardants and their environmental impact. Its structure, featuring bromine atoms, makes it particularly effective in inhibiting the radical chain reactions that contribute to combustion processes. Scientific studies involving TBPP have explored its interaction with various materials, including polymers and textiles, to assess how it modifies their flammability and thermal degradation properties. Researchers use TBPP to explain the pathways through which brominated flame retardants influence the formation of char, a critical factor in fire resistance. These studies help in developing more effective and environmentally safer fire retardants by comparing the efficacy and stability of brominated compounds against newer, less hazardous alternatives. Moreover, TBPP has been a subject of interest in environmental chemistry, where its persistence and bioaccumulation potential are examined. Studies focus on its breakdown products and their interactions with living organisms at the cellular level, aiming to understand the environmental fate of brominated flame retardants. Through these investigations, TBPP contributes significantly to the field of environmental safety and material science, providing insights into the balance between fire safety and ecological impact.


TBPP (CAS 126-72-7) References

  1. Organ-specific DNA damage of tris(2,3-dibromopropyl)-phosphate and its diester metabolite in the rat.  |  Søderlund, EJ., et al. 1992. Chem Biol Interact. 82: 195-207. PMID: 1568270
  2. Flame retardant tris(1,3-dichloro-2-propyl)phosphate (TDCPP) toxicity is attenuated by N-acetylcysteine in human kidney cells.  |  Killilea, DW., et al. 2017. Toxicol Rep. 4: 260-264. PMID: 28959647
  3. Detection of tris(2,3-dibromopropyl) phosphate and other organophosphorous compounds in Arctic rivers.  |  Allan, IJ., et al. 2018. Environ Sci Pollut Res Int. 25: 28730-28737. PMID: 30121771
  4. Multiplexed quantitative evaluation on mitochondrial toxicity of tris (2,3-dibromopropyl) phosphate in hepatocyte.  |  Ma, X., et al. 2021. Ecotoxicol Environ Saf. 221: 112425. PMID: 34146984
  5. Comparative genotoxicity and nephrotoxicity studies of the two halogenated flame retardants tris(1,3-dichloro-2-propyl)phosphate and tris(2,3-dibromopropyl)phosphate.  |  Søderlund, EJ., et al. 1985. Acta Pharmacol Toxicol (Copenh). 56: 20-9. PMID: 3883695
  6. Mutagenicity of bis- and mono-(2,3-dibromopropyl)phosphate, and their salts used as flame retardants, in the Salmonella/microsome system.  |  Nakamura, A., et al. 1983. Mutat Res. 117: 1-8. PMID: 6339901
  7. Comparative genotoxicity studies of the flame retardant tris(2,3-dibromopropyl)phosphate and possible metabolites.  |  Holme, JA., et al. 1983. Mutat Res. 124: 213-24. PMID: 6686285
  8. Metabolism and disposition of the flame retardant tris(2,3-dibromopropyl)phosphate in the rat.  |  Nomeir, AA. and Matthews, HB. 1983. Toxicol Appl Pharmacol. 67: 357-69. PMID: 6845365
  9. Metabolism and genotoxicity of the halogenated alkyl compound tris(2,3-dibromopropyl)phosphate.  |  van Beerendonk, GJ., et al. 1994. Hum Exp Toxicol. 13: 861-5. PMID: 7718306

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

TBPP, 100 mg

sc-251104A
100 mg
$184.00

TBPP, 250 mg

sc-251104
250 mg
$337.00