Tauroursodeoxycholic Acid Dihydrate (CAS 14605-22-2 (anhydrous))

Tauroursodeoxycholic acid dihydrate, often abbreviated as TUDCA, is a bile acid derivative with significant relevance in biochemical research. Primarily, it is used as a tool to study the physiological and pathological roles of bile acids in cellular processes. In the realm of molecular biology, Tauroursodeoxycholic Acid Dihydrate is employed to investigate its cytoprotective properties, particularly its ability to stabilize membranes and mitigate endoplasmic reticulum stress, which is implicated in a variety of cellular dysfunctions. Additionally, it′s a chaperone molecule that aids in the proper folding of proteins, making it useful for studying protein misfolding diseases. Tauroursodeoxycholic Acid Dihydrate also provides insights into the mechanisms of cholestasis and the regulation of bile acid synthesis and secretion. Its role in the modulation of cell signaling pathways, such as those involving the farnesoid X receptor, also contributes to our understanding of metabolic regulation. Furthermore, Tauroursodeoxycholic Acid Dihydrate is utilized in the production of reference standards for the calibration of analytical instruments in the quantification of bile acids.