Taurolithocholic Acid Sodium Salt (CAS 6042-32-6)

Taurolithocholic acid sodium salt, a bile acid derivative, is extensively utilized in scientific research to explore various aspects of bile acid physiology and pathophysiology. Its mechanism of action primarily involves its role in lipid digestion and absorption in the gastrointestinal tract. Taurolithocholic acid sodium salt interacts with bile acid receptors and transporters, influencing lipid metabolism, cholesterol homeostasis, and bile acid signaling pathways. Research indicates its involvement in regulating hepatic lipid metabolism, cholesterol synthesis, and bile acid synthesis pathways, providing insights into metabolic disorders such as obesity, non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease. Additionally, taurolithocholic acid sodium salt serves as a valuable tool in studying bile acid-induced toxicity, cellular stress responses, and apoptosis mechanisms. Furthermore, its impact on gut microbiota composition and intestinal barrier function underscores its relevance in gastrointestinal health and disease. Taurolithocholic acid sodium salt is also utilized in experimental models to investigate bile acid-related disorders, cholestasis, and liver injury, contributing to advancements in understanding the molecular mechanisms underlying these conditions. Overall, taurolithocholic acid sodium salt plays a crucial role in elucidating the complex interplay between bile acids, lipid metabolism, and gastrointestinal physiology in research settings.