Taurocholic Acid (CAS 81-24-3)
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Taurocholic acid is a bile acid that plays a role in the digestion and absorption of fats in the small intestine. It functions as an emulsifier, aiding in the breakdown of dietary fats into smaller droplets, which increases the surface area for lipase enzymes to act upon. This process facilitates the hydrolysis of triglycerides into fatty acids and monoglycerides, which can be absorbed by the intestinal mucosa. Taurocholic acid forms micelles with the products of fat digestion, allowing for their transport across the aqueous environment of the intestinal lumen to the surface of the enterocytes. Once at the cell membrane, the fatty acids and monoglycerides are taken up by the enterocytes and reassembled into triglycerides, which are packaged into chylomicrons for transport through the lymphatic system. Taurocholic acid aids in the solubilization and absorption of fat-soluble vitamins, such as vitamins A, D, E, and K. Taurocholic acid′s role in the digestion and absorption of fats is essential for the maintenance of proper nutrient balance and energy homeostasis.
Taurocholic Acid (CAS 81-24-3) References
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- Long-term intervention of taurocholic acid over-expressing in cholestatic liver disease inhibits the growth of hepatoma cells. | Zhang, X., et al. 2020. Cell Mol Biol (Noisy-le-grand). 66: 65-70. PMID: 32415929
- Taurocholic acid lowers the inflammatory response of gingival fibroblasts, epithelial cells, and macrophages. | Talebian, R., et al. 2020. J Oral Sci. 62: 335-339. PMID: 32581181
- Taurocholic Acid and Glycocholic Acid Inhibit Inflammation and Activate Farnesoid X Receptor Expression in LPS-Stimulated Zebrafish and Macrophages. | Ge, X., et al. 2023. Molecules. 28: PMID: 36903252
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Taurocholic Acid, 5 mg | sc-220189 | 5 mg | $81.00 | |||
Taurocholic Acid, 25 mg | sc-220189A | 25 mg | $318.00 |