Molecular structure of Taurochenodeoxycholic Acid, Sodium Salt, CAS Number: 6009-98-9
Taurochenodeoxycholic Acid, Sodium Salt (CAS 6009-98-9)
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Application:
Taurochenodeoxycholic Acid, Sodium Salt is a detergent for the solubilization of lipids and membrane-bound proteins
CAS Number:
6009-98-9
Purity:
≥97%
Molecular Weight:
521.69
Molecular Formula:
C26H44NO6S•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Taurochenodeoxycholic Acid, Sodium Salt is a detergent useful for the solubilization of lipids and membrane-bound proteins. Taurochenodeoxycholic Acid inhibits Na+-dependent taurocholate transport in the intestine. Taurochenodeoxycholic Acid (TCDCA) is a bile acid compound that is formed by the conjugation of chenodeoxycholic acid (chenodiol), which is a primary bile acid, with taurine. TCDCA is used as a detergent to solubilize lipids and membrane-bound proteins, and it also inhibits Na+-dependent taurocholate transport in the intestine.
Taurochenodeoxycholic Acid, Sodium Salt (CAS 6009-98-9) References
- 6alpha-hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes. | Araya, Z. and Wikvall, K. 1999. Biochim Biophys Acta. 1438: 47-54. PMID: 10216279
- Taurochenodeoxycholic acid induces apoptosis of fibroblast-like synoviocytes. | Li, L., et al. 2013. Eur J Pharmacol. 706: 36-40. PMID: 23510744
- Taurochenodeoxycholic acid induces NR8383 cells apoptosis via PKC/JNK-dependent pathway. | Wang, X., et al. 2016. Eur J Pharmacol. 786: 109-115. PMID: 27268718
- Discovery of glycocholic acid and taurochenodeoxycholic acid as phenotypic biomarkers in cholangiocarcinoma. | Song, WS., et al. 2018. Sci Rep. 8: 11088. PMID: 30038332
- Taurochenodeoxycholic Acid Inhibited AP-1 Activation via Stimulating Glucocorticoid Receptor. | Li, L., et al. 2019. Molecules. 24: PMID: 31835494
- Biliary Microbiota and Bile Acid Composition in Cholelithiasis. | Petrov, VA., et al. 2020. Biomed Res Int. 2020: 1242364. PMID: 32714973
- Small intestinal taurochenodeoxycholic acid-FXR axis alters local nutrient-sensing glucoregulatory pathways in rats. | Waise, TMZ., et al. 2021. Mol Metab. 44: 101132. PMID: 33264656
- Taurochenodeoxycholic acid mediates cAMP-PKA-CREB signaling pathway. | Qi, YC., et al. 2020. Chin J Nat Med. 18: 898-906. PMID: 33357720
- Transcriptome investigation of anti-inflammation and immuno-regulation mechanism of taurochenodeoxycholic acid. | Bao, L., et al. 2021. BMC Pharmacol Toxicol. 22: 23. PMID: 33926569
- Taurochenodeoxycholic acid inhibits the proliferation and invasion of gastric cancer and induces its apoptosis. | Zhang, D., et al. 2022. J Food Biochem. 46: e13866. PMID: 34278593
- Taurochenodeoxycholic Acid Increases cAMP Content via Specially Interacting with Bile Acid Receptor TGR5. | Qi, Y., et al. 2021. Molecules. 26: PMID: 34885648
- Serum concentration of taurochenodeoxycholic acid predicts clinically significant portal hypertension. | Žížalová, K., et al. 2023. Liver Int. 43: 888-895. PMID: 36433660
- Taurochenodeoxycholic acid ameliorates and ursodeoxycholic acid exacerbates small intestinal inflammation. | Uchida, A., et al. 1997. Am J Physiol. 272: G1249-57. PMID: 9176237
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Taurochenodeoxycholic Acid, Sodium Salt, 1 g | sc-281162 | 1 g | $707.00 |