Taspase 1 Antibody (B-7): sc-390934
- Taspase 1 Antibody (B-7) is a mouse monoclonal IgA κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 89-130 within an internal region of Taspase 1 of human origin
- recommended for detection of Taspase 1 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Taspase 1 Antibody (B-7). This work is in progress.
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Taspase 1 Antibody (B-7) is a mouse monoclonal IgA antibody that detects Taspase 1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Taspase 1 is a crucial endopeptidase composed of 420 amino acids, known for its role in cleaving specific substrates after aspartate residues, which is essential for the processing of MLL (myeloid/lymphoid or mixed-lineage leukemia) and the accurate expression of the Hox A gene cluster. Taspase 1 undergoes autoproteolytic processing post-translation, resulting in the formation of two subunits, alpha and beta, that reassemble into a multimeric structure necessary for enzymatic activity. Taspase 1′s importance extends beyond enzymatic function; this protein is located in the nucleus, where Taspase 1 plays a pivotal role in gene regulation and cellular differentiation. The gene encoding Taspase 1 is situated on human chromosome 20, which harbors approximately 2% of the human genome and contains genes linked to various neurological disorders, including Creutzfeldt-Jakob disease and amyotrophic lateral sclerosis. With diverse applications and critical biological functions, anti-Taspase 1 antibody (B-7) serves as an invaluable tool for researchers studying gene expression and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Taspase 1 Antibody (B-7) | sc-390934 | 200 µg/ml | $322.00 | |||
Taspase 1 (B-7) Neutralizing Peptide | sc-390934 P | 100 µg/0.5 ml | $69.00 |