Date published: 2026-3-10

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TAPSO, Sodium Salt (CAS 105140-25-8)

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Alternate Names:
3-(N-tris[Hydroxymethyl]methylamino)-2-hydroxypropanesulfonic acid
Application:
TAPSO, Sodium Salt is a zwitterionic biological buffer, pH range: 7.0-8.2.
CAS Number:
105140-25-8
Molecular Weight:
281.3
Molecular Formula:
C7H16NO7SNa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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TAPSO, Sodium Salt, is a chemical compound widely utilized in scientific research for its unique properties and diverse applications across various disciplines. One of its primary mechanisms of action lies in its buffering capacity, making it an essential component in biochemical and molecular biology studies. TAPSO, or N-tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium salt, serves as a zwitterionic buffer with a pKa near physiological pH, allowing for precise control of pH in biological assays and cell culture experiments. Its ability to maintain a stable pH environment is crucial for maintaining the integrity and activity of biological molecules, such as enzymes and proteins, during experimental procedures. Moreover, TAPSO is utilized in electrophoresis techniques, where it serves as a running buffer for the separation of biomolecules based on size and charge. Additionally, TAPSO has found applications in protein purification and chromatography, where it acts as a mobile phase buffer for the isolation and purification of biomolecules. Furthermore, TAPSO is employed in the preparation of biochemical reagents and analytical standards, ensuring the accuracy and reproducibility of experimental results. Overall, TAPSO, Sodium Salt, continues to be a valuable compound in scientific research, owing to its buffering capabilities and broad utility in various research applications spanning biochemistry, molecular biology, electrophoresis, protein purification, and analytical chemistry.


TAPSO, Sodium Salt (CAS 105140-25-8) References

  1. Hydrogen ion buffers for biological research.  |  Good, NE., et al. 1966. Biochemistry. 5: 467-77. PMID: 5942950

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

TAPSO, Sodium Salt, 25 g

sc-296446
25 g
$56.00

TAPSO, Sodium Salt, 100 g

sc-296446A
100 g
$240.00

TAPSO, Sodium Salt, 1 kg

sc-296446B
1 kg
$1200.00

TAPSO, Sodium Salt, 2 kg

sc-296446C
2 kg
$2100.00