Tamsulosin Hydrochloride (CAS 106463-17-6)
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Tamsulosin Hydrochloride is a selective antagonist of the α1-adrenergic receptor. In the realm of research, its mechanism of action is particularly intriguing as it specifically targets the α1 receptors located in smooth muscle tissue, leading to muscle relaxation. This specificity is for studies focusing on the modulation of smooth muscle activity, offering a precise tool for dissecting the pathways and effects of adrenergic receptor signaling. The compound′s ability to selectively bind to and inhibit these receptors without significantly affecting other adrenergic receptor subtypes makes it an invaluable asset in pharmacodynamic and pharmacokinetic studies. It aids in the exploration of the autonomic nervous system′s regulation of smooth muscle, providing insights into the underlying mechanisms of muscle contraction and relaxation. By elucidating these complex biological processes, Tamsulosin Hydrochloride contributes significantly to the advancement of our understanding of smooth muscle physiology and the development of more targeted research methodologies.
Tamsulosin Hydrochloride (CAS 106463-17-6) References
- Hemodialysis in diabetic patients with chronic renal failure. | Ma, KW., et al. 1975. Ann Intern Med. 83: 215-7. PMID: 1147455
- Expression of alpha1-adrenoceptor subtype mRNA as a predictor of the efficacy of subtype selective alpha1-adrenoceptor antagonists in the management of benign prostatic hyperplasia. | Kojima, Y., et al. 2008. J Urol. 179: 1040-6. PMID: 18206918
- Effectiveness of tamsulosin hydrochloride and its mechanism in improving nocturia associated with lower urinary tract symptoms/benign prostatic hyperplasia. | Yoshida, M., et al. 2010. Neurourol Urodyn. 29: 1276-81. PMID: 20878997
- Evaluating tamsulosin hydrochloride-released microparticles prepared using single-step matrix coating. | Maeda, A., et al. 2011. Int J Pharm. 408: 84-90. PMID: 21291970
- Preparation and in vivo evaluation of spray dried matrix type controlled-release microparticles of tamsulosin hydrochloride for orally disintegrating tablet. | Park, CW., et al. 2012. Drug Dev Ind Pharm. 38: 1179-87. PMID: 22200122
- Impact of four loci on serum tamsulosin hydrochloride concentration. | Takata, R., et al. 2013. J Hum Genet. 58: 21-6. PMID: 23151678
- Spectrophotometric estimation of tamsulosin hydrochloride by acid-dye method. | Shrivastava, A., et al. 2011. Pharm Methods. 2: 53-60. PMID: 23781431
- Smart spectrophotometric assessment of tamsulosin hydrochloride and tadalafil in their new pharmaceutical formulation for treatment of benign prostatic hyperplasia and erectile dysfunction. | Rezk, MR., et al. 2020. Spectrochim Acta A Mol Biomol Spectrosc. 227: 117547. PMID: 31734571
- Quantification of Tamsulosin Hydrochloride and Solifenacin Succinate by Discriminative Derivative Synchronous Emission Spectroscopy. | Naraparaju, S., et al. 2018. Turk J Pharm Sci. 15: 149-155. PMID: 32454654
- Application of reusable flat-membrane in electro-membrane extraction for tamsulosin hydrochloride determination in cleaning validation samples of sterile production line equipment by RP-HPLC. | Hakak Zade, E. and Mollahosseini, A. 2021. Eur J Pharm Sci. 161: 105793. PMID: 33691156
- Sensitive detection of tamsulosin hydrochloride based on dual-emission ratiometric fluorescence probe consisting of amine-carbon quantum dots and rhodamine B. | Mousavi, A., et al. 2021. Sci Rep. 11: 20805. PMID: 34675291
- Tamsulosin and risk of priapism: A causality assessment using Austin Bradford Hill Criteria. | Russom, M., et al. 2022. Pharmacol Res Perspect. 10: e00934. PMID: 35170870
- The effectiveness of tamsulosin hydrochloride with terazosin combination therapy for chronic prostatitis Type-III b. | Duan, B. and Wang, X. 2022. Pak J Med Sci. 38: 595-599. PMID: 35480502
- Green & Sensitive pH-dependent Spectrofluorimetric Assay of Tamsulosin Hydrochloride and Tadalafil in their New Combined Formulation for Benign Prostatic Hyperplasia: Application to Spiked Human Plasma. | Abdel Moneim, MM. 2022. J Fluoresc. 32: 1581-1590. PMID: 35576092
- [Discovery and development of tamsulosin hydrochloride, a new alpha 1-adrenoceptor antagonist]. | Takenaka, T., et al. 1995. Yakugaku Zasshi. 115: 773-89. PMID: 8531059
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tamsulosin Hydrochloride, 10 mg | sc-203289 | 10 mg | $132.00 | |||
Tamsulosin Hydrochloride, 25 mg | sc-203289A | 25 mg | $260.00 |