TAMRA-Azide-PEG-Biotin (CAS 1797415-74-7)
See product citations (1)
QUICK LINKS
TAMRA-Azide-PEG-Biotin is a biotin PEG linker that incorporates an azide moiety that enables click chemistry-mediated labeling of alkyne-labeled proteins. It is a used reagent for the development and affinity purification of alkyne-labeled molecules. Hydrophilic PEG spacers increase solubility in aqueous media and reduce spatial site resistance when bound to streptavidin antibiotin molecules.PEG linkers can be used for the development of antibody drug couplers. Biotin was able to enrich proteins efficiently. Finally, carboxytetramethylrhodamine (TAMRA) fluorophores remain attached to proteins after elution from the streptavidin antibiotin resin and are used for sensitive detection of labeled proteins.
TAMRA-Azide-PEG-Biotin (CAS 1797415-74-7) References
- Avidin-biotin-PEG-CPA complexes as potential EPR-directed therapeutic protein carriers: preparation and characterization. | Ke, S., et al. 2007. Bioconjug Chem. 18: 1644-50. PMID: 17705554
- Y-shaped biotin-conjugated poly (ethylene glycol)-poly (epsilon-caprolactone) copolymer for the targeted delivery of curcumin. | Zhu, W., et al. 2015. J Colloid Interface Sci. 443: 1-7. PMID: 25526295
- The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. | Bersuker, K., et al. 2019. Nature. 575: 688-692. PMID: 31634900
- Kinase Photoaffinity Labeling Reveals Low Selectivity Profile of the IRE1 Targeting Imidazopyrazine-Based KIRA6 Inhibitor. | Korovesis, D., et al. 2020. ACS Chem Biol. 15: 3106-3111. PMID: 33290055
- Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting. | Rufo, N., et al. 2022. Cell Death Differ. 29: 230-245. PMID: 34453119
- Basic studies on heterobifunctional biotin-PEG conjugates with a 3-(4-pyridyldithio)propionyl marker on the second terminus. | Kaiser, K., et al. 1997. Bioconjug Chem. 8: 545-51. PMID: 9258454
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TAMRA-Azide-PEG-Biotin, 5 mg | sc-496240 | 5 mg | $546.00 | |||
TAMRA-Azide-PEG-Biotin, 25 mg | sc-496240A | 25 mg | $2244.00 |