Molecular structure of Talniflumate, CAS Number: 66898-62-2
Talniflumate (CAS 66898-62-2)
Alternate Names:
Lomucin; Somalgen; Talniflumatum
Application:
Talniflumate is an inhibitor of Cox and Cl-/HCO3- exchange
CAS Number:
66898-62-2
Purity:
≥98%
Molecular Weight:
414.34
Molecular Formula:
C21H13F3N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and release in animal models and cell culture. Talniflumate possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. Talniflumate increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome.
Talniflumate (CAS 66898-62-2) References
1. Knight, D., 2004. Curr. Opin. Invest. Drugs. 5: 557-562.2. Walker, N.M., et al. 2006. J. Pharmacol. Exp. Ther. 317: 275-283.
Inhibitor of:
Cox, and TMEM16C.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Talniflumate, 10 mg | sc-203706 | 10 mg | $85.00 | |||
Talniflumate, 50 mg | sc-203706A | 50 mg | $359.00 |