TAF II p170 Antibody (BTA3D61): sc-81391

TAF II p170 Antibody (BTA3D61) is a mouse monoclonal IgG1 antibody that detects TAF II p170 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). TAF II p170 Antibody (BTA3D61) is available as a non-conjugated anti-TAF II p170 antibody (BTA3D61). TAF II p170 protein plays a crucial role in the formation of the transcription factor complex TFIID, which is essential for the initiation of gene transcription. TFIID is a multisubunit complex that not only binds to the TATA box of promoters but also interacts with various transcriptional activators, thereby facilitating the assembly of the preinitiation complex. TAF II p170 within this complex is particularly important as TAF II p170 contributes to the stability and functionality of TFIID, allowing for both basal and regulated transcription. Additionally, TAF II p170 has been shown to possess significant (d)ATPase activity, which is vital for the energy-dependent processes involved in transcription initiation. Anti-TAF II p170 antibody (BTA3D61) enables researchers to gain insights into the mechanisms of transcription regulation and the role of TAFs in gene expression across different species.

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TAF II p170 Antibody (BTA3D61) References:

1. Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau).  |  Takada, R., et al. 1992. Proc Natl Acad Sci U S A. 89: 11809-13. PMID: 1465404
2. Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation.  |  Dynlacht, BD., et al. 1991. Cell. 66: 563-76. PMID: 1907890
3. Five intermediate complexes in transcription initiation by RNA polymerase II.  |  Buratowski, S., et al. 1989. Cell. 56: 549-61. PMID: 2917366
4. Multiple factors required for accurate initiation of transcription by purified RNA polymerase II.  |  Matsui, T., et al. 1980. J Biol Chem. 255: 11992-6. PMID: 7440580
5. Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation.  |  Ruppert, S., et al. 1993. Nature. 362: 175-9. PMID: 7680771
6. The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1.  |  Hisatake, K., et al. 1993. Nature. 362: 179-81. PMID: 8450888
7. Cloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila.  |  van der Knaap, JA., et al. 1997. Proc Natl Acad Sci U S A. 94: 11827-32. PMID: 9342322

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-TAF II p170 Antibody (BTA3D61) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-TAF II p170 Antibody (BTA3D61) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

TAF II p170 Antibody (BTA3D61) Specifications

Alternate Product Name: TAF II p170

Product Clone Name: BTA3D61

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: TAF II p170

Epitope Species: human

Product Reactivity/Detection: TAF II p170

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 1.0% stabilizer protein

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for TAF II p170 Antibody (BTA3D61): N/A