T98G Cell Lysate: sc-2294

T98G Cell Lysate is derived from T98G cells, a human glioblastoma multiforme (GBM) cell line established from a 61-year-old male patient. This lysate is extensively used in cancer research to explore the molecular mechanisms underlying GBM, a highly aggressive brain tumor. T98G cells are characterized by their resistance to certain chemotherapeutic agents and harbor mutations in key genes such as TP53 and CDKN2A. Researchers utilize T98G Cell Lysate to investigate the expression, phosphorylation, and interactions of proteins involved in critical signaling pathways like PI3K/AKT, MAPK/ERK, and mTOR using techniques such as western blotting, immunoprecipitation, and mass spectrometry. This lysate is valuable for examining the cellular mechanisms of tumor growth, survival, invasion, and resistance to apoptosis. Additionally, T98G Cell Lysate aids in studying the effects of various chemical compounds on signaling pathways, providing insights into the cellular processes that drive glioblastoma progression. By comparing T98G lysates with those from normal glial cells, scientists can identify specific molecular alterations associated with GBM. This research is crucial for advancing our understanding of glioblastoma biology, facilitating the identification of potential molecular targets for further exploration in the field of cancer research.

T98G Cell Lysate References:

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