T-FABP Antibody (B-4): sc-390196

T-FABP Antibody (B-4) is a mouse monoclonal IgG3 kappa light chain antibody that detects T-FABP of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-T-FABP antibody (B-4) is available as the non-conjugated form. T-FABP, also known as FABP9 or Testis lipid-binding protein, plays a crucial role in the transport and metabolism of fatty acids within testicular germ cells during spermatogenesis. T-FABP facilitates the uptake and intracellular trafficking of fatty acids, which are essential for energy production and cellular signaling in developing germ cells. By mediating the transport of these lipids, T-FABP contributes to the proper development and maturation of sperm, highlighting its importance in male fertility. Expression of T-FABP remains tightly regulated and specific to testicular tissues, underscoring its role in reproductive biology. T-FABP′s ability to interact with various hydrophobic ligands further emphasizes its significance in lipid metabolism and cellular function.

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T-FABP Antibody (B-4) References:

1. The fatty acid transport function of fatty acid-binding proteins.  |  Storch, J. and Thumser, AE. 2000. Biochim Biophys Acta. 1486: 28-44. PMID: 10856711
2. Expression of testicular fatty acid-binding protein PERF 15 during germ cell apoptosis.  |  Kido, T. and Namiki, H. 2000. Dev Growth Differ. 42: 359-66. PMID: 10969735
3. Unravelling the significance of cellular fatty acid-binding proteins.  |  Glatz, JF. and Storch, J. 2001. Curr Opin Lipidol. 12: 267-74. PMID: 11353329
4. The testicular fatty acid binding protein PERF15 regulates the fate of germ cells in PERF15 transgenic mice.  |  Kido, T., et al. 2005. Dev Growth Differ. 47: 15-24. PMID: 15740583
5. The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism.  |  Chmurzyńska, A. 2006. J Appl Genet. 47: 39-48. PMID: 16424607
6. Quantification of PERF 15 mRNA in tissue sections from rat testes.  |  Kogami, T., et al. 2006. Acta Histochem Cytochem. 39: 183-92. PMID: 17327905
7. Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3.  |  Liu, ZZ., et al. 2021. Autophagy. 17: 2766-2782. PMID: 33143524
8. FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging.  |  Lee, SM., et al. 2020. Nat Commun. 11: 5661. PMID: 33168829
9. The oxidized phospholipid PGPC impairs endothelial function by promoting endothelial cell ferroptosis via FABP3.  |  Chen, S., et al. 2024. J Lipid Res. 65: 100499. PMID: 38218337
10. Cytoplasmic fatty acid-binding proteins: their structure and genes.  |  Veerkamp, JH. and Maatman, RG. 1995. Prog Lipid Res. 34: 17-52. PMID: 7644552
11. Molecular cloning and structural analysis of the gene encoding PERF 15 protein present in the perinuclear theca of the rat spermatozoa.  |  Pouresmaeili, F., et al. 1997. Biol Reprod. 57: 655-9. PMID: 9283004
12. Analysis of the protein composition of the mouse sperm perinuclear theca and characterization of its major protein constituent.  |  Korley, R., et al. 1997. Biol Reprod. 57: 1426-32. PMID: 9408250

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-T-FABP Antibody (B-4) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-T-FABP Antibody (B-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

T-FABP Antibody (B-4) Specifications

Alternate Product Name: FABP9

Product Clone Name: B-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids:

Epitope Target: T-FABP

Epitope Species: mouse

Product Reactivity/Detection: T-FABP

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for T-FABP Antibody (B-4): P: Blocking Peptide