Date published: 2026-5-1

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t-Butyl 4-fluorobenzoate (CAS 58656-98-7)

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CAS Number:
58656-98-7
Molecular Weight:
196.22
Molecular Formula:
C11H13FO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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t-Butyl 4-fluorobenzoate, a colorless and odorless liquid, that is slightly soluble in water but readily integrates with polar solvents like ethanol and methanol. This compound is recognized for potential biological activities, exhibiting properties like antibacterial and antifungal activities. It catalyzes the arylation of tert-butyl amines with glycinamide ribonucleotides. These properties are linked primarily due to the presence of the fluoro group which enhances its bioactivity. It is used in scientific studies as a reagent and as an intermediate substance, and also a fundamental building block in synthesizing various organic compounds. Additionally, it finds application in the manufacturing of polymers and resins, attributed to its distinctive characteristics.


t-Butyl 4-fluorobenzoate (CAS 58656-98-7) References

  1. Nickel-catalyzed amination of aryl fluorides with primary amines.  |  Harada, T., et al. 2018. Chem Commun (Camb). 54: 1718-1721. PMID: 29250630
  2. Reagents for reversible coupling of proteins to the active centres of trypsin-like serine proteinases.  |  Kalindjian, SB. and Smith, RA. 1987. Biochem J. 248: 409-13. PMID: 2963619
  3. 2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity.  |  Martín-López, J., et al. 2021. Pharmaceuticals (Basel). 14: PMID: 34959721

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

t-Butyl 4-fluorobenzoate, 5 g

sc-311541
5 g
$84.00

t-Butyl 4-fluorobenzoate, 25 g

sc-311541A
25 g
$296.00