Synaptogyrin-2 Antibody (5C3): sc-517053
- Synaptogyrin-2 Antibody (5C3) is a mouse monoclonal IgG3 κ Synaptogyrin-2 antibody provided at 100 µg/ml
- raised against amino acids 168-224 representing partial length Synaptogyrin-2 of human origin
- recommended for detection of Synaptogyrin-2 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Synaptogyrin-2 Antibody (5C3). This work is in progress.
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Synaptogyrin-2 Antibody (5C3) is a mouse monoclonal IgG3 kappa light chain antibody that detects Synaptogyrin-2 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-Synaptogyrin-2 antibody (5C3) is available as a non-conjugated format. Synaptogyrin-2, also known as cellugyrin, plays a crucial role in regulating membrane traffic, particularly in non-neuronal cells, due to its unique structure that includes a tyrosine-phosphorylated C-terminal cytoplasmic tail. This post-translational modification influences Synaptogyrin-2′s interactions with various signaling pathways and cellular processes, thereby impacting the overall dynamics of membrane trafficking and synaptic function. The synaptogyrin family, which includes Synaptogyrin-1 and Synaptogyrin-3, consists of integral membrane proteins characterized by four transmembrane regions, with Synaptogyrin-2 being the ubiquitous isoform. While Synaptogyrin-1 is primarily associated with presynaptic vesicles in neuronal cells, Synaptogyrin-2′s broader expression pattern highlights its importance in diverse cellular contexts. Synaptogyrin-2 (5C3) antibody is an essential tool for researchers studying synaptic vesicle dynamics and membrane trafficking mechanisms in human cells.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Synaptogyrin-2 Antibody (5C3) References:
- Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells. | Belfort, GM. and Kandror, KV. 2003. J Biol Chem. 278: 47971-8. PMID: 12928441
- Characterization of synaptogyrin 3 as a new synaptic vesicle protein. | Belizaire, R., et al. 2004. J Comp Neurol. 470: 266-81. PMID: 14755516
- Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats. | Hitchcock, IS., et al. 2004. Neurosci Lett. 362: 196-9. PMID: 15158013
- Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis. | Masliah, E., et al. 2004. J Neuroimmunol. 157: 163-75. PMID: 15579294
- Cellugyrin induces biogenesis of synaptic-like microvesicles in PC12 cells. | Belfort, GM., et al. 2005. J Biol Chem. 280: 7262-72. PMID: 15590695
- Rat retinal dopaminergic neurons: differential maturation of somatodendritic and axonal compartments. | Witkovsky, P., et al. 2005. J Comp Neurol. 481: 352-62. PMID: 15593337
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Synaptogyrin-2 Antibody (5C3) | sc-517053 | 100 µg/ml | $322.00 |