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Suppressin Antibody (E-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects Suppressin protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Suppressin antibody (E-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a crucial transcription factor involved in embryonic development, playing a significant role in mediating cell fate and embryonic pattern formation. Suppressin is primarily localized in the nucleus, where Suppressin interacts with other proteins such as LMO4 and CLIM-2, highlighting Suppressin′s importance in transcriptional regulation. Suppressin contains a SAND domain and a C-terminal MYND-type zinc finger, which are essential for function and interactions. Several isoforms of Suppressin exist due to alternative splicing, and in certain cell types, Suppressin can be secreted to inhibit cell proliferation by arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may confer a growth advantage, potentially leading to the development and progression of neoplasia, making Suppressin a promising target for cancer therapy.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Suppressin Antibody (E-5) | sc-514180 | 200 µg/ml | $316.00 | |||
Suppressin Antibody (E-5): m-IgG Fc BP-HRP Bundle | sc-531055 | 200 µg Ab; 10 µg BP | $354.00 | |||
Suppressin Antibody (E-5): m-IgGκ BP-HRP Bundle | sc-524638 | 200 µg Ab, 40 µg BP | $354.00 | |||
Suppressin Antibody (E-5): m-IgG1 BP-HRP Bundle | sc-544375 | 200 µg Ab; 20 µg BP | $354.00 | |||
Suppressin Antibody (E-5) AC | sc-514180 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Suppressin Antibody (E-5) HRP | sc-514180 HRP | 200 µg/ml | $316.00 | |||
Suppressin Antibody (E-5) FITC | sc-514180 FITC | 200 µg/ml | $330.00 | |||
Suppressin Antibody (E-5) PE | sc-514180 PE | 200 µg/ml | $343.00 | |||
Suppressin Antibody (E-5) Alexa Fluor® 488 | sc-514180 AF488 | 200 µg/ml | $357.00 | |||
Suppressin Antibody (E-5) Alexa Fluor® 546 | sc-514180 AF546 | 200 µg/ml | $357.00 | |||
Suppressin Antibody (E-5) Alexa Fluor® 594 | sc-514180 AF594 | 200 µg/ml | $357.00 | |||
Suppressin Antibody (E-5) Alexa Fluor® 647 | sc-514180 AF647 | 200 µg/ml | $357.00 | |||
Suppressin Antibody (E-5) Alexa Fluor® 680 | sc-514180 AF680 | 200 µg/ml | $357.00 | |||
Suppressin Antibody (E-5) Alexa Fluor® 790 | sc-514180 AF790 | 200 µg/ml | $357.00 | |||
Suppressin (E-5) Neutralizing Peptide | sc-514180 P | 100 µg/0.5 ml | $68.00 |