SUMO-1 Antibody (66AT1273.94): sc-130275
- SUMO-1 Antibody (66AT1273.94) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- raised against purified recombinant SUMO-1 of human origin
- recommended for detection of SUMO-1 of mouse, rat and human origin by WB, IP and ELISA
- See SUMO-1 (D-11): sc-5308 for SUMO-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SUMO-1 Antibody (66AT1273.94). This work is in progress.
SUMO-1 Antibody (66AT1273.94) is a mouse monoclonal IgG1 antibody that detects SUMO-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). SUMO-1, a member of the small ubiquitin-related modifier (SUMO) protein family, plays a crucial role in various cellular processes, including nuclear transport, transcriptional regulation, and apoptosis, by modifying target proteins through a process known as sumoylation. Unlike ubiquitin, which primarily tags proteins for degradation, SUMO-1 modifies proteins to enhance stability and functionality, making SUMO-1 essential for maintaining cellular homeostasis. SUMO-1 is predominantly localized to the nuclear membrane and nuclear bodies, where SUMO-1 interacts with key regulatory proteins such as IκBa, MDM2, and p53, influencing their activity and stability. Notably, SUMO-1′s ability to regulate these proteins underscores SUMO-1′s importance in cellular signaling pathways and potential implications in diseases such as cancer and neurodegenerative disorders. Anti-SUMO-1 antibody (66AT1273.94) is an invaluable tool for researchers investigating the dynamic roles of sumoylation in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SUMO-1 Antibody (66AT1273.94) | sc-130275 | 100 µg/ml | $322.00 |