Molecular structure of Sumatriptan-d6, CAS Number: 1020764-38-8
Sumatriptan-d6 (CAS 1020764-38-8)
See product citations (3)
Alternate Names:
3-[2-(Dimethyl-d6-amino)-ethyl]-N-methyl-1H-indole-5-methanesulfonamide
Application:
Sumatriptan-d6 is A serotonin 5HT1-receptor agonist
CAS Number:
1020764-38-8
Molecular Weight:
301.44
Molecular Formula:
C14H15D6N3O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sumatriptan-d6 is in analytical chemistry for the development and validation of analytical methods, particularly in mass spectrometry. This deuterated version of sumatriptan serves as an internal standard, facilitating the accurate quantification of sumatriptan in biological samples through techniques such as liquid chromatography-mass spectrometry (LC-MS). Some may utilize Sumatriptan-d6 to achieve more precise measurements by correcting for sample preparation losses and matrix effects that might occur during analysis. The compound is in pharmacokinetic studies to trace the metabolic pathways and distribution of sumatriptan in various biological systems.
Sumatriptan-d6 (CAS 1020764-38-8) References
- The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family. | Dos Santos Pereira, JN., et al. 2014. AAPS J. 16: 1247-58. PMID: 25155823
- Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP. | Kashihara, Y., et al. 2017. J Pharm Sci. 106: 2688-2694. PMID: 28322941
- GR43175, a selective agonist for the 5-HT1-like receptor in dog isolated saphenous vein. | Humphrey, PP., et al. 1988. Br J Pharmacol. 94: 1123-32. PMID: 2850055
- Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A. | Panfen, E., et al. 2019. Drug Metab Dispos. 47: 1352-1360. PMID: 31427432
- Transfer of triptans into human breast milk and estimation of infant drug exposure through breastfeeding. | Amundsen, S., et al. 2021. Basic Clin Pharmacol Toxicol. 128: 795-804. PMID: 33730376
- Amino acids in transmembrane helix 1 confer major functional differences between human and mouse orthologs of the polyspecific membrane transporter OCT1. | Meyer, MJ., et al. 2022. J Biol Chem. 298: 101974. PMID: 35469921
- Evaluation of the Impact of Ritlecitinib on Organic Cation Transporters Using Sumatriptan and Biomarkers as Probes. | Wang, X., et al. 2023. J Clin Pharmacol.. PMID: 36807251
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Serotonin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sumatriptan-d6, 1 mg | sc-220175 | 1 mg | $198.00 | |||
Sumatriptan-d6, 10 mg | sc-220175A | 10 mg | $2497.00 |