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Sumatriptan (CAS 103628-46-2)

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Alternate Names:
3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide
Application:
Sumatriptan is a serotonin 5HT1-receptor agonist
CAS Number:
103628-46-2
Molecular Weight:
295.4
Molecular Formula:
C14H21N3O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sumatriptan is a SR-1A (serotonin 5HT1-receptor) agonist.


Sumatriptan (CAS 103628-46-2) References

  1. Influence of sumatriptan on gastric fundus tone and on the perception of gastric distension in man.  |  Tack, J., et al. 2000. Gut. 46: 468-73. PMID: 10716674
  2. Effect of early intervention with sumatriptan on migraine pain: retrospective analyses of data from three clinical trials.  |  Cady, RK., et al. 2000. Clin Ther. 22: 1035-48. PMID: 11048903
  3. Tolerability of sumatriptan: clinical trials and post-marketing experience.  |  Welch, KM., et al. 2000. Cephalalgia. 20: 687-95. PMID: 11167896
  4. Sumatriptan plus metoclopramide in triptan-nonresponsive migraineurs.  |  Schulman, EA. and Dermott, KF. 2003. Headache. 43: 729-33. PMID: 12890127
  5. Neurogenic versus vascular mechanisms of sumatriptan and ergot alkaloids in migraine.  |  Moskowitz, MA. 1992. Trends Pharmacol Sci. 13: 307-11. PMID: 1329294
  6. Migraine pain associated with middle cerebral artery dilatation: reversal by sumatriptan.  |  Friberg, L., et al. 1991. Lancet. 338: 13-7. PMID: 1676084
  7. Sumatriptan-naproxen for acute treatment of migraine: a randomized trial.  |  Brandes, JL., et al. 2007. JAMA. 297: 1443-54. PMID: 17405970
  8. Mucoadhesive bilayered patches for administration of sumatriptan succinate.  |  Shidhaye, SS., et al. 2008. AAPS PharmSciTech. 9: 909-16. PMID: 18679806
  9. The safety of sumatriptan and naratriptan in pregnancy: what have we learned?  |  Cunnington, M., et al. 2009. Headache. 49: 1414-22. PMID: 19804390
  10. Dihydroergotamine, ergotamine, methysergide and sumatriptan - basic science in relation to migraine treatment.  |  Dahlöf, C. and Maassen Van Den Brink, A. 2012. Headache. 52: 707-14. PMID: 22444161
  11. Comparative neuropharmacology of dihydroergotamine and sumatriptan (GR 43175).  |  McCarthy, BG. and Peroutka, SJ. 1989. Headache. 29: 420-2. PMID: 2547733
  12. Effect of subcutaneous sumatriptan, a selective 5HT1 agonist, on the systemic, pulmonary, and coronary circulation.  |  MacIntyre, PD., et al. 1993. Circulation. 87: 401-5. PMID: 8381056
  13. SUMATRIPTAN: a receptor-targeted treatment for migraine.  |  Moskowitz, MA. and Cutrer, FM. 1993. Annu Rev Med. 44: 145-54. PMID: 8386498
  14. Subcutaneous sumatriptan in the acute treatment of cluster headache: a dose comparison study. The Sumatriptan Cluster Headache Study Group.  |  Ekbom, K., et al. 1993. Acta Neurol Scand. 88: 63-9. PMID: 8396833
  15. Sumatriptan for migraine attacks in children: a randomized placebo-controlled study. Do children with migraine respond to oral sumatriptan differently from adults?  |  Hämäläinen, ML., et al. 1997. Neurology. 48: 1100-3. PMID: 9109909

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sumatriptan, 50 mg

sc-473020
50 mg
$460.00