Date published: 2025-10-17

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Sulphanilamide (CAS 63-74-1)

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Alternate Names:
p-Aminobenzenesulfonamide; 4-(Aminosulfonyl)aniline
Application:
Sulphanilamide is The active metabolite of the antibacterial dye, Sulfamidochrysoidine
CAS Number:
63-74-1
Molecular Weight:
172.20
Molecular Formula:
C6H8N2O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sulphanilamide is a compound of chemical significance, primarily recognized for its foundational role in the development of sulfonamide compounds. Outside of this scope, it remains a subject of study for its chemical properties and reactions. In research, sulphanilamide is explored for its role as a molecular scaffold in the synthesis of dyes, as its sulfonamide group can readily bind to other molecules, creating a variety of compounds with potential applications in industrial processes. Its basic aromatic amine structure also allows for investigations into electrophilic substitution reactions, which are fundamental in teaching organic chemistry principles related to reaction mechanisms. Additionally, sulphanilamide′s ability to form hydrogen bonds makes it a useful compound for studying intermolecular interactions, which are in the design and development of new materials and chemical sensors.


Sulphanilamide (CAS 63-74-1) References

  1. Antibiotic sulfanilamide biodegradation by acclimated microbial populations.  |  Liao, X., et al. 2016. Appl Microbiol Biotechnol. 100: 2439-47. PMID: 26563551
  2. Towards a molecular level understanding of the sulfanilamide-soil organic matter-interaction.  |  Ahmed, AA., et al. 2016. Sci Total Environ. 559: 347-355. PMID: 27088516
  3. N-doped Cu-MOFs for efficient electrochemical determination of dopamine and sulfanilamide.  |  Chen, S., et al. 2020. J Hazard Mater. 390: 122157. PMID: 31999959
  4. Enhanced-oxidation of sulfanilamide in groundwater using combination of calcium peroxide and pyrite.  |  Kim, JG., et al. 2021. J Hazard Mater. 419: 126514. PMID: 34323727
  5. Quantum chemical study the on interaction between sulfanilamide drug and MgO nanocluster.  |  Sang, X. and Derakhshandeh, M. 2021. J Mol Model. 27: 283. PMID: 34515848
  6. Visible light photocatalytic degradation of sulfanilamide enhanced by Mo doping of BiOBr nanoflowers.  |  Wu, Y., et al. 2022. J Hazard Mater. 424: 127563. PMID: 34736201
  7. Microbially-mediated synthesis of activated carbon derived from cottonseed husks for enhanced sulfanilamide removal.  |  Xu, T., et al. 2022. J Hazard Mater. 426: 127811. PMID: 34844799
  8. Removal of sulfanilamide by tailor-made magnetic metal-ceramic nanocomposite adsorbents.  |  Sannino, F., et al. 2022. J Environ Manage. 310: 114701. PMID: 35217443
  9. Sulfanilamide Regulates Flowering Time through Expression of the Circadian Clock Gene LUX.  |  Hirohata, A., et al. 2022. Plant Cell Physiol. 63: 649-657. PMID: 35238923
  10. 3D-printed electrode an affordable sensor for sulfanilamide monitoring in breast milk, synthetic urine, and pharmaceutical formulation samples.  |  Lisboa, TP., et al. 2022. Talanta. 247: 123610. PMID: 35649326
  11. Mechanistic investigation into flow-through electrochemical oxidation of sulfanilamide for groundwater using a graphite anode.  |  Kim, JG., et al. 2022. Chemosphere. 307: 136106. PMID: 35988764
  12. A solvent-mediated conformational switch in sulfanilamide.  |  Mato, S., et al. 2022. Phys Chem Chem Phys. 24: 24032-24038. PMID: 36106463
  13. A pencil graphite-based disposable device for electrochemical monitoring of sulfanilamide in honey and water samples.  |  Lisboa, TP., et al. 2022. Anal Methods. 14: 3867-3874. PMID: 36129347
  14. The Role of Nanoengineered Biochar Activated with Fe for Sulfanilamide Removal from Soils and Water.  |  Gámiz, B., et al. 2022. Molecules. 27: PMID: 36364242

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sulphanilamide, 100 g

sc-208410
100 g
$42.00

Sulphanilamide, 250 g

sc-208410A
250 g
$78.00

Sulphanilamide, 1 kg

sc-208410B
1 kg
$245.00