Date published: 2026-2-10

1-800-457-3801

SCBT Portrait Logo
Seach Input

Sulmazole (CAS 73384-60-8)

0.0(0)
Write a reviewAsk a question

Alternate Names:
2-(2-Methoxy-4-[methylsulfinyl]phenyl)-1H-imidazo(4,5-b)pyridine
Application:
Sulmazole is An A1 adenosine receptor antagonist
CAS Number:
73384-60-8
Molecular Weight:
287.34
Molecular Formula:
C14H13N3O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Sulmazole is an A1 adenosine receptor antagonist. Sulmazole is an imidazopyridine that is 1H-imidazo[4,5-b]pyridine which is substituted at position 2 by a 2-methoxy-4-(methylsulfinyl)phenyl group. An A1 adenosine receptor antagonist, it was formerly used as a cardiotonic agent. It has a role as a inhibitor and an adenosine A1 receptor antagonist. It is an imidazopyridine and a sulfoxide.


Sulmazole (CAS 73384-60-8) References

  1. Pharmacological characterization of a new Ca(2+) sensitizer.  |  Dorigo, P., et al. 2000. J Pharmacol Exp Ther. 295: 994-1004. PMID: 11082434
  2. Effects of the specific phosphodiesterase inhibitors on alloxan-induced diabetic rabbit cavernous tissue in vitro.  |  Utkan, T., et al. 2001. Int J Impot Res. 13: 24-30. PMID: 11313837
  3. 'Low' concentrations of sodium fluoride inhibit neurotransmitter release from the guinea-pig superior cervical ganglion.  |  Borasio, PG., et al. 2004. Neurosci Lett. 364: 86-9. PMID: 15196683
  4. Selective reduction of methylsulfinyl-containing compounds by mammalian MsrA suggests a strategy for improved drug efficacy.  |  Lee, BC., et al. 2011. ACS Chem Biol. 6: 1029-35. PMID: 21823615
  5. New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 2.  |  Colucci, WS., et al. 1986. N Engl J Med. 314: 349-58. PMID: 2418353
  6. Evaluation of activity inotropic of a new steroid derivative using an isolated rat heart model.  |  Lauro, FV., et al. 2014. Int J Clin Exp Med. 7: 1223-32. PMID: 24995077
  7. Novel myosin-based therapies for congenital cardiac and skeletal myopathies.  |  Ochala, J. and Sun, YB. 2016. J Med Genet. 53: 651-4. PMID: 27412953
  8. Identification of cardioprotective drugs by medium-scale in vivo pharmacological screening on a Drosophila cardiac model of Friedreich's ataxia.  |  Palandri, A., et al. 2018. Dis Model Mech. 11: PMID: 29898895
  9. Phosphodiesterase Inhibitors Revert Axonal Dystrophy in Friedreich's Ataxia Mouse Model.  |  Mollá, B., et al. 2019. Neurotherapeutics. 16: 432-449. PMID: 30761510
  10. Investigation mechanisms between normal, developing and regenerating livers for regenerative liver drug design.  |  Wong, SW., et al. 2019. Regen Med. 14: 359-387. PMID: 31204905
  11. Rapid Construction of an Imidazo[4,5-b]pyridine Skeleton from 2-Chloro-3-nitropyridine via Tandem Reaction in H2O-IPA Medium.  |  Padmaja, RD., et al. 2018. ACS Omega. 3: 4583-4590. PMID: 31458681
  12. Keloid Biomarkers and Their Correlation With Immune Infiltration.  |  Yin, X., et al. 2022. Front Genet. 13: 784073. PMID: 35719372
  13. Unbiased transcriptome mapping and modeling identify candidate genes and compounds of osteoarthritis.  |  Cao, H., et al. 2022. Front Pharmacol. 13: 888533. PMID: 36034872
  14. Differential effects of phosphodiesterase inhibitors on accumulation of cyclic AMP in isolated ventricular cardiomyocytes.  |  Kelso, EJ., et al. 1995. Biochem Pharmacol. 49: 441-52. PMID: 7872950
  15. Effects of milrinone and sulmazole on left ventricular mechanoenergetics in canine hearts.  |  Hata, K., et al. 1996. J Card Fail. 2: 203-13. PMID: 8891859

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sulmazole, 50 mg

sc-236956
50 mg
$213.00