N-Hydroxy Sulfamethoxazole (CAS 114438-33-4)

N-Hydroxy Sulfamethoxazole, a metabolite of sulfamethoxazole, finds application in diverse scientific research endeavors. As a member of the sulfonamide family, it contributes to the synthesis of various molecules and serves as a intermediate in the creation of pharmaceuticals, pesticides, and other compounds. Its utility extends to the creation of peptides, peptidomimetics, and peptidomimetic analogs. Additionally, it facilitates the synthesis of organometallic compounds like palladium and platinum complexes. Acting as a nucleophile during molecule synthesis, N-Hydroxy Sulfamethoxazole interacts with various functional groups such as alkenes, alkynes, and aryl halides. It also engages with oxidizing agents like hydrogen peroxide and sodium hypochlorite. This reaction is believed to follow a radical mechanism, where the N-Hydroxy Sulfamethoxazole radical abstracts a hydrogen atom from the substrate, leading to the formation of an intermediate. Subsequently, a series of rearrangements occur to yield the desired product.