Molecular structure of Sulfaguanidine, CAS Number: 57-67-0
Sulfaguanidine (CAS 57-67-0)
Alternate Names:
4-Amino-N-(aminoiminomethyl)benzenesulfonamide
CAS Number:
57-67-0
Molecular Weight:
214.24
Molecular Formula:
C7H10N4O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sulfaguanidine is an inhibitor of DHFR. Sulfaguanidine is an antibacterial drug belonging to the sulfonamide class. Additionally, it has been extensively examined in in vitro studies to assess its antibacterial properties. These investigations have yielded compelling evidence, showcasing the efficacy of sulfaguanidine against a diverse array of bacteria, encompassing both Gram-positive and Gram-negative species, such as Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae. Moreover, in cell culture experiments, sulfaguanidine has been the subject of exploration to elucidate its potential anti-inflammatory effects.
Sulfaguanidine (CAS 57-67-0) References
- Preparation, characterization and biological activity of Fe(III), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and UO(2)(II) complexes of new cyclodiphosph(V)azane of sulfaguanidine. | Sharaby, CM. 2005. Spectrochim Acta A Mol Biomol Spectrosc. 62: 326-34. PMID: 16257733
- Sulfadimethoxine and sulfaguanidine: their sorption potential on natural soils. | Białk-Bielińska, A., et al. 2012. Chemosphere. 86: 1059-65. PMID: 22197018
- Hydrolysis of sulphonamides in aqueous solutions. | Białk-Bielińska, A., et al. 2012. J Hazard Mater. 221-222: 264-74. PMID: 22579461
- Preparation and application of sulfaguanidine-imprinted polymer on solid-phase extraction of pharmaceuticals from water. | Mutavdžić Pavlović, D., et al. 2015. Talanta. 131: 99-107. PMID: 25281079
- Synthesis of novel sulfonamide analogs containing sulfamerazine/sulfaguanidine and their biological activities. | Aday, B., et al. 2016. J Enzyme Inhib Med Chem. 31: 1005-10. PMID: 26327456
- Three-component synthesis and carbonic anhydrase inhibitory properties of novel octahydroacridines incorporating sulfaguanidine scaffold. | Ulus, R., et al. 2016. J Enzyme Inhib Med Chem. 31: 63-69. PMID: 27237188
- Sulfaguanidine cocrystals: Synthesis, structural characterization and their antibacterial and hemolytic analysis. | Abidi, SSA., et al. 2018. J Pharm Biomed Anal. 149: 351-357. PMID: 29145096
- Rapid detection of sulfaguanidine in fish by using a photonic crystal molecularly imprinted polymer. | Li, L., et al. 2019. Food Chem. 281: 57-62. PMID: 30658765
- Synthesis, Characterization, and Inhibition Study of Novel Substituted Phenylureido Sulfaguanidine Derivatives as α-Glycosidase and Cholinesterase Inhibitors. | Akocak, S., et al. 2021. Chem Biodivers. 18: e2000958. PMID: 33620128
- Lanthanide type of cerium sulfide embedded carbon nitride composite modified electrode for potential electrochemical detection of sulfaguanidine. | Priscillal, IJD., et al. 2021. Mikrochim Acta. 188: 313. PMID: 34458931
- Design, Synthesis and Evaluation of Novel Antimicrobial Polymers Based on the Inclusion of Polyethylene Glycol/TiO2 Nanocomposites in Cyclodextrin as Drug Carriers for Sulfaguanidine. | Dardeer, HM., et al. 2022. Polymers (Basel). 14: PMID: 35054634
- Sulfaguanidine nanofiltration active layer towards anti-adhesive and antimicrobial attributes for desalination and dye removal. | Zhang, HL., et al. 2019. RSC Adv. 9: 20715-20727. PMID: 35515551
- Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydrase inhibitory potency and selectivity. | Allam, HA., et al. 2023. J Enzyme Inhib Med Chem. 38: 2201403. PMID: 37078174
- Nature of Luminescence and Pharmacological Activity of Sulfaguanidine. | Tchaikovskaya, O., et al. 2023. Molecules. 28: PMID: 37241901
- ZnO and Au nanoparticles supported highly sensitive and selective electrochemical sensor based on molecularly imprinted polymer for sulfaguanidine and sulfamerazine detection. | Koçak, İ. 2023. J Pharm Biomed Anal. 234: 115518. PMID: 37336038
Inhibitor of:
DHFR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sulfaguanidine, 25 g | sc-251083 | 25 g | $51.00 | |||
Sulfaguanidine, 100 g | sc-251083A | 100 g | $92.00 |