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Sulfadiazine sodium salt (CAS 547-32-0)

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Alternate Names:
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide sodium salt
CAS Number:
547-32-0
Purity:
≥98%
Molecular Weight:
272.26
Molecular Formula:
C10H9N4NaO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sulfadiazine sodium salt is used in microbiological research to study the mechanisms of sulfonamide action against bacteria. This compound is for understanding how these agents inhibit the synthesis of folic acid in bacterial cells, a vital process for their growth and reproduction. Researchers utilize Sulfadiazine sodium salt to investigate bacterial resistance mechanisms, which helps in exploring how bacteria adapt to and evade certain chemical agents. In addition, it is used in studies that assess the environmental impact of sulfonamides, particularly their behavior and breakdown in aquatic ecosystems. Sulfadiazine sodium salt also serves as a reference substance in the development of analytical methods for detecting similar compounds in environmental samples.


Sulfadiazine sodium salt (CAS 547-32-0) References

  1. Study of stability of sulfadiazine sodium injection. I. Determination of solubility of sulfadiazine sodium as a function of pH in several parenteral solvent systems.  |  AUTIAN, J. and HOM, FS. 1956. J Am Pharm Assoc Am Pharm Assoc. 45: 608-11. PMID: 13357365
  2. Drug release kinetics and transport mechanisms from semi-interpenetrating networks of gelatin and poly(ethylene glycol) diacrylate.  |  Fu, Y. and Kao, WJ. 2009. Pharm Res. 26: 2115-24. PMID: 19554430
  3. Eco-toxic effects of sulfadiazine sodium, sulfamonomethoxine sodium and enrofloxacin on wheat, Chinese cabbage and tomato.  |  Jin, C., et al. 2009. Ecotoxicology. 18: 878-85. PMID: 19554446
  4. A new approach for the evaluation of niosomes as effective transdermal drug delivery systems.  |  Muzzalupo, R., et al. 2011. Eur J Pharm Biopharm. 79: 28-35. PMID: 21303691
  5. Molecular interaction of ctDNA and HSA with sulfadiazine sodium by multispectroscopic methods and molecular modeling.  |  Geng, S., et al. 2013. Luminescence. 28: 785-92. PMID: 23322489
  6. Great efficacy of sulfachloropyrazine-sodium against acute murine toxoplasmosis.  |  Zeng, YB., et al. 2012. Asian Pac J Trop Biomed. 2: 70-5. PMID: 23569838
  7. Development and validation of a stability-indicating HPLC method for the simultaneous determination of sulfadiazine sodium and trimethoprim in injectable solution formulation.  |  Ghanem, MM. and Abu-Lafi, SA. 2013. Sci Pharm. 81: 167-82. PMID: 23641336
  8. Novel gel-niosomes formulations as multicomponent systems for transdermal drug delivery.  |  Tavano, L., et al. 2013. Colloids Surf B Biointerfaces. 110: 281-8. PMID: 23732806
  9. Niosomes containing hydroxyl additives as percutaneous penetration enhancers: effect on the transdermal delivery of sulfadiazine sodium salt.  |  Muzzalupo, R., et al. 2014. Colloids Surf B Biointerfaces. 123: 207-12. PMID: 25260220
  10. Efficient visible-light photocatalytic degradation of sulfadiazine sodium with hierarchical Bi₇O₉I₃under solar irradiation.  |  Xu, M., et al. 2015. Water Sci Technol. 72: 2122-31. PMID: 26675999
  11. A novel antibiotic wastewater degradation technique combining cavitating jets impingement with multiple synergetic methods.  |  Tao, Y., et al. 2018. Ultrason Sonochem. 44: 36-44. PMID: 29680622
  12. Sulfadiazine Sodium Ameliorates the Metabolomic Perturbation in Mice Infected with Toxoplasma gondii.  |  Zhou, CX., et al. 2019. Antimicrob Agents Chemother. 63: PMID: 31383652
  13. Exploration of synthesizing fluorescent silicon nanoparticles and label-free detection of sulfadiazine sodium.  |  Bai, Y., et al. 2020. Talanta. 220: 121410. PMID: 32928425
  14. Comparison of different S-doped biochar materials to activate peroxymonosulfate for efficient degradation of antibiotics.  |  Zhang, Y. and Zhao, J. 2022. Chemosphere. 308: 136442. PMID: 36126742
  15. Gallic Acid Restores the Sulfonamide Sensitivity of Multidrug-Resistant Streptococcus suis via Polypharmaceology Mechanism.  |  Qu, Q., et al. 2023. J Agric Food Chem. 71: 6894-6907. PMID: 37125728

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sulfadiazine sodium salt, 25 g

sc-251082
25 g
$37.00

Good Day... Dear, I did not get expiry date or retest date in COA , could you help me.

Asked by: keerthi
All of our products are warrantied for one year from the date purchased. If a CoA with an expiration date is needed, please inquire with Technical Service or your local distributor, and one will be provided to you. Please note that all CoAs are lot-specific.
Answered by: Tech Service
Date published: 2019-03-12
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Rated 5 out of 5 by from WangWang, Z. et al. (PubMed 18473212) produced a new monoclonal antibody (Mab) against sulphamerazine (SMR) and a fluorescence polarisation immunoassay based on the Mab was developed and optimized for the simultaneous qualitative screening of SMR, sulphamethazine, and Sulfadiazine. -SCBT Publication Review
Date published: 2015-06-25
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Sulfadiazine sodium salt is rated 5.0 out of 5 by 1.
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