Sucrose 6,1′-Dicarboxylic Acid (CAS 155533-83-8)

Sucrose 6,1′-Dicarboxylic Acid is a bifunctional derivative of sucrose that contains carboxylic acid groups at both the 6- and 1′-positions of the molecule. This dual substitution significantly alters the properties of the sugar, making it a valuable research tool in carbohydrate chemistry and biochemistry. The compound has been widely used to study enzymatic specificity and catalytic mechanisms due to its structural modification, serving as a substrate analog for glycosyltransferase and glycosidase assays. By understanding how these modifications impact enzyme interactions, researchers gain insights into substrate recognition, enzyme kinetics, and catalytic pathways. The compound′s carboxyl groups provide useful sites for chemical conjugation, allowing it to be linked to other biomolecules or used as a precursor for synthesizing more complex glycoconjugates. This ability facilitates glycan mapping and structural analysis in glycobiology research. Sucrose 6,1′-Dicarboxylic Acid also aids in developing analytical methods for carbohydrate profiling, especially when distinguishing different sucrose derivatives. Its unique structure makes it a marker in chromatography and mass spectrometry. Furthermore, this compound serves as a precursor for functionalizing sugars in synthetic biology, where researchers design custom glycans to probe the biological role of carbohydrate modifications. As a result, it contributes significantly to carbohydrate-active enzyme research and carbohydrate chemistry.