Sucrose 1′-Carboxylic Acid (CAS 150787-99-8)

Sucrose 1′-Carboxylic Acid is a modified sugar derivative formed by the esterification of the 1′-hydroxyl group of sucrose with a carboxyl group. This structure modifies sucrose′s chemical properties, expanding its applicability in carbohydrate chemistry and biochemistry research. The functionalization of sucrose enables scientists to investigate carbohydrate metabolism and develop specific assays for studying enzymatic specificity and catalytic mechanisms. For example, this derivative is often employed to analyze glycosyl hydrolase and glycosyltransferase activities, providing a model substrate to characterize these enzymes′ substrate binding and cleavage properties. In analytical chemistry, sucrose 1′-Carboxylic Acid is a key standard for chromatographic studies aimed at separating and identifying complex carbohydrate mixtures. The compound′s unique structure aids in distinguishing it from other sucrose derivatives, making it a valuable marker in carbohydrate profiling. Furthermore, in synthetic biology and glycobiology research, its modified functional group can serve as a useful precursor for the production of more complex saccharides. This aids in mapping glycan structures and understanding the influence of specific modifications on glycan biosynthesis. Overall, sucrose 1′-Carboxylic Acid is instrumental for researchers exploring the intricacies of carbohydrate metabolism and enzymology, where it aids in refining our knowledge of carbohydrate-active enzymes and sugar metabolism pathways.