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Sucralose-d6 (CAS 1459161-55-7)

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Alternate Names:
Sucralose-d6 is also known as Trichlorosucrose-d6.
Application:
Sucralose-d6 is a useful, isotopically labeled analog of sucralose
CAS Number:
1459161-55-7
Molecular Weight:
403.67
Molecular Formula:
C12H13D6Cl3O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sucralose-d6 is a useful isotopically labeled analog of the artificial sweetener sucralose. It is a modified version of sucralose in which six hydrogen atoms have been replaced with deuterium, a stable isotope of hydrogen. This labeling is useful for tracing the metabolic fate of sucralose in biological systems or chemical reactions using various analytical techniques such as NMR spectroscopy. Sucralose-d6 is used as a research tool in fields such as pharmacology, metabolism, and food science, where it can be used to study the pharmacokinetics and metabolic fate of sucralose in vitro.


Sucralose-d6 (CAS 1459161-55-7) References

  1. Sucralose screening in European surface waters using a solid-phase extraction-liquid chromatography-triple quadrupole mass spectrometry method.  |  Loos, R., et al. 2009. J Chromatogr A. 1216: 1126-31. PMID: 19131070
  2. Understanding consumption-related sucralose emissions - A conceptual approach combining substance-flow analysis with sampling analysis.  |  Neset, TS., et al. 2010. Sci Total Environ. 408: 3261-9. PMID: 20447681
  3. Occurrence and suitability of sucralose as an indicator compound of wastewater loading to surface waters in urbanized regions.  |  Oppenheimer, J., et al. 2011. Water Res. 45: 4019-27. PMID: 21665241
  4. Multiresidue method for the analysis of emerging contaminants in wastewater by ultra performance liquid chromatography-time-of-flight mass spectrometry.  |  Nurmi, J. and Pellinen, J. 2011. J Chromatogr A. 1218: 6712-9. PMID: 21840011
  5. Online solid phase extraction liquid chromatography tandem mass spectrometry (SPE-LC-MS/MS) method for the determination of sucralose in reclaimed and drinking waters and its photo degradation in natural waters from South Florida.  |  Batchu, SR., et al. 2013. Chem Cent J. 7: 141. PMID: 23965251
  6. EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents.  |  Loos, R., et al. 2013. Water Res. 47: 6475-87. PMID: 24091184
  7. Monitoring for contaminants of emerging concern in drinking water using POCIS passive samplers.  |  Metcalfe, C., et al. 2014. Environ Sci Process Impacts. 16: 473-81. PMID: 24531237
  8. Sucralose induces biochemical responses in Daphnia magna.  |  Eriksson Wiklund, AK., et al. 2014. PLoS One. 9: e92771. PMID: 24699280
  9. Rapid ultra-trace analysis of sucralose in multiple-origin aqueous samples by online solid-phase extraction coupled to high-resolution mass spectrometry.  |  Batchu, SR., et al. 2015. Anal Bioanal Chem. 407: 3717-25. PMID: 25772563
  10. Effects of artificial sweeteners on metal bioconcentration and toxicity on a green algae Scenedesmus obliquus.  |  Hu, H., et al. 2016. Chemosphere. 150: 285-293. PMID: 26915590
  11. Estimating removals of contaminants of emerging concern from wastewater treatment plants: The critical role of wastewater hydrodynamics.  |  Baalbaki, Z., et al. 2017. Chemosphere. 178: 439-448. PMID: 28342992
  12. Pharmaceuticals, illicit drugs and their metabolites in fish from Argentina: Implications for protected areas influenced by urbanization.  |  Ondarza, PM., et al. 2019. Sci Total Environ. 649: 1029-1037. PMID: 30308876
  13. Assessing accuracy, precision and selectivity using quality controls for non-targeted analysis.  |  Ng, B., et al. 2020. Sci Total Environ. 713: 136568. PMID: 31955085
  14. Assessment of Sucralose, Caffeine and Acetaminophen as Anthropogenic Tracers in Aquatic Systems Across Florida.  |  Henderson, A., et al. 2020. Bull Environ Contam Toxicol. 105: 351-357. PMID: 32749513
  15. Saccharin and Sucralose Protect the Glomerular Microvasculature In Vitro against VEGF-Induced Permeability.  |  Enuwosa, E., et al. 2021. Nutrients. 13: PMID: 34444906

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sucralose-d6, 1 mg

sc-220145
1 mg
$612.00

Sucralose-d6, 1 mg

sc-220145-CW
1 mg
$765.00

Sucralose-d6, 10 mg

sc-220145A
10 mg
$3742.00

What is different about the item with "CW" in the product number?

Asked by: EllenMC
Thank you for your question. We also offer a certified weight version of this compound with a very precise amount of the product. Feel free to directly contact our technical service team for additional information.
Answered by: Tech Support Europe
Date published: 2023-03-17
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Rated 5 out of 5 by from Various publications cite the use of SucraloseVarious publications cite the use of Sucralose-d6, an isotopically labeled analog of sucralose, as a useful marker in studies of sucralose. -SCBT Publication Review
Date published: 2015-07-10
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Sucralose-d6 is rated 5.0 out of 5 by 1.
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