Molecular structure of Succinyl coenzyme A sodium salt, CAS Number: 108347-97-3
Succinyl coenzyme A sodium salt (CAS 108347-97-3)
See product citations (3)
Alternate Names:
Succinyl coenzyme A sodium salt is also known as Succinyl-CoA.
Application:
Succinyl coenzyme A sodium salt is an intermediate in the citric acid cycle, eventually to be converted into succinate.
CAS Number:
108347-97-3
Purity:
≥85%
Molecular Weight:
867.61 (non sodium salt)
Molecular Formula:
C25H40N7O19P3S•xNa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Succinyl coenzyme A sodium salt is an intermediate in the cycle of citric acid. In this cycle, Succinyl coenzyme A sodium salt is converted to succinate, a metabolic intermediate for various biological purposes. Succinyl coenzyme A sodium salt along with glycine are capable of forming δ-aminolevulinic acid, a vital first step in porphyrin and heme synthesis. A vitamin B12 deficiency can lead to a Succinyl coenzyme A sodium salt deficiency, thereby disrupting heme and energy production. In other words, a Succinyl coenzyme A sodium salt deficiency is tantamount to neuromotor dysfunction.
Succinyl coenzyme A sodium salt (CAS 108347-97-3) References
- Comparison of two methods for the measurement of rat liver methylmalonyl-coenzyme A mutase activity: HPLC and radioisotopic assays. | Gaire, D., et al. 1999. J Nutr Biochem. 10: 56-62. PMID: 15539251
- Epimerase (Msed_0639) and mutase (Msed_0638 and Msed_2055) convert (S)-methylmalonyl-coenzyme A (CoA) to succinyl-CoA in the Metallosphaera sedula 3-hydroxypropionate/4-hydroxybutyrate cycle. | Han, Y., et al. 2012. Appl Environ Microbiol. 78: 6194-202. PMID: 22752162
- Porphyrin and heme metabolism and the porphyrias. | Bonkovsky, HL., et al. 2013. Compr Physiol. 3: 365-401. PMID: 23720291
- Optimization and validation of a reversed-phase high performance liquid chromatography method for the measurement of bovine liver methylmalonyl-coenzyme a mutase activity. | Ouattara, B., et al. 2013. BMC Biochem. 14: 25. PMID: 24131771
- Direct biosynthesis of adipic acid from a synthetic pathway in recombinant Escherichia coli. | Yu, JL., et al. 2014. Biotechnol Bioeng. 111: 2580-6. PMID: 24895214
- Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines. | Gibson, GE., et al. 2015. J Neurochem. 134: 86-96. PMID: 25772995
- 3-Sulfinopropionyl-coenzyme A (3SP-CoA) desulfinase from Advenella mimigardefordensis DPN7(T): crystal structure and function of a desulfinase with an acyl-CoA dehydrogenase fold. | Schürmann, M., et al. 2015. Acta Crystallogr D Biol Crystallogr. 71: 1360-72. PMID: 26057676
- Mitochondrial Probe Methyltriphenylphosphonium (TPMP) Inhibits the Krebs Cycle Enzyme 2-Oxoglutarate Dehydrogenase. | Elkalaf, M., et al. 2016. PLoS One. 11: e0161413. PMID: 27537184
- Comprehensive Analysis of the Lysine Succinylome and Protein Co-modifications in Developing Rice Seeds. | Meng, X., et al. 2019. Mol Cell Proteomics. 18: 2359-2372. PMID: 31492684
- SIRT5 impairs aggregation and activation of the signaling adaptor MAVS through catalyzing lysine desuccinylation. | Liu, X., et al. 2020. EMBO J. 39: e103285. PMID: 32301534
- Structure, Biosynthesis, and Biological Activity of Succinylated Forms of Bacteriocin BacSp222. | Śmiałek, J., et al. 2021. Int J Mol Sci. 22: PMID: 34200765
- Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation. | Trefely, S., et al. 2022. Mol Cell. 82: 447-462.e6. PMID: 34856123
- Biotin controls intestinal stem cell mitosis and host-microbiome interactions. | Neophytou, C. and Pitsouli, C. 2022. Cell Rep. 38: 110505. PMID: 35263602
- Discovery, Biosynthesis and Biological Activity of a Succinylated Myxochelin from the Myxobacterial Strain MSr12020. | Okoth, DA., et al. 2022. Microorganisms. 10: PMID: 36296235
- ACYL Phosphates As Enzyme-Bound Intermediates In The Biosynthesis Of Glutamine, Glutathione, Succinyl Coenzyme A, And Carbamyl Phosphate | Alton Meister. 1968. Transactions Of The New York Academy Of Sciences. 30: 1157-1180.
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Enzyme.Activator of:
ME3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Succinyl coenzyme A sodium salt, 5 mg | sc-215917 | 5 mg | $290.00 | |||
Succinyl coenzyme A sodium salt, 25 mg | sc-215917A | 25 mg | $1085.00 |