Molecular structure of Succinic semialdehyde, CAS Number: 692-29-5
Succinic semialdehyde (CAS 692-29-5)
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Alternate Names:
β-Formylpropionic Acid; 3-Formylpropanoic Acid; Succinic Acid Semialdehyde; γ-Oxybutyric Acid
CAS Number:
692-29-5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Succinic semialdehyde (SSA) is synthesized through the oxidation of succinic acid and the metabolism of L-tryptophan. It acts as a metabolic byproduct in the degradation pathway, which is fundamental to understanding cellular metabolism. This compound is also employed in the synthesis of various polymers, where its reactivity as an aldehyde is exploited to form new chemical bonds. In the field of biotechnology, this compound′s transformation by various microorganisms is studied to explore bioconversion processes, potentially aiding in the development of bio-based production methods for complex chemicals.
Succinic semialdehyde (CAS 692-29-5) References
- Succinic semialdehyde dehydrogenase deficiency in children and adults. | Pearl, PL., et al. 2003. Ann Neurol. 54 Suppl 6: S73-80. PMID: 12891657
- Succinic semialdehyde dehydrogenase deficiency (SSADH) (4-hydroxybutyric aciduria, gamma-hydroxybutyric aciduria). | Gordon, N. 2004. Eur J Paediatr Neurol. 8: 261-5. PMID: 15341910
- Succinic semialdehyde dehydrogenase deficiency: lessons from mice and men. | Pearl, PL., et al. 2009. J Inherit Metab Dis. 32: 343-52. PMID: 19172412
- Succinic semialdehyde dehydrogenase: biochemical-molecular-clinical disease mechanisms, redox regulation, and functional significance. | Kim, KJ., et al. 2011. Antioxid Redox Signal. 15: 691-718. PMID: 20973619
- [Succinic semialdehyde dehydrogenase deficiency]. | Deng, XL., et al. 2011. Zhongguo Dang Dai Er Ke Za Zhi. 13: 740-2. PMID: 21924025
- [Succinic semialdehyde dehydrogenase deficiency: an inheritable neurometabolic disease]. | Gahr, M., et al. 2013. Fortschr Neurol Psychiatr. 81: 154-61. PMID: 23516105
- Succinic semialdehyde dehydrogenase deficiency (SSADHD): Pathophysiological complexity and multifactorial trait associations in a rare monogenic disorder of GABA metabolism. | Malaspina, P., et al. 2016. Neurochem Int. 99: 72-84. PMID: 27311541
- Temporal metabolomics in dried bloodspots suggests multipathway disruptions in aldh5a1-/- mice, a model of succinic semialdehyde dehydrogenase deficiency. | Brown, M., et al. 2019. Mol Genet Metab. 128: 397-408. PMID: 31699650
- Succinic Semialdehyde Dehydrogenase Deficiency: An Update. | Didiášová, M., et al. 2020. Cells. 9: PMID: 32093054
- The characterization of psychotic symptoms in succinic semialdehyde dehydrogenase deficiency: a review. | Colijn, MA. 2020. Psychiatr Genet. 30: 153-161. PMID: 33165204
- Succinic semialdehyde dehydrogenase deficiency presenting with central hypothyroidism. | Alghamdi, MA., et al. 2021. Clin Case Rep. 9: 229-235. PMID: 33489165
- Understanding the Molecular Mechanisms of Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD): Towards the Development of SSADH-Targeted Medicine. | Lee, HHC., et al. 2022. Int J Mol Sci. 23: PMID: 35269750
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Succinic semialdehyde, 2.5 mg | sc-397497 | 2.5 mg | $326.00 | |||
Succinic semialdehyde, 5 mg | sc-397497A | 5 mg | $490.00 | |||
Succinic semialdehyde, 25 mg | sc-397497B | 25 mg | $2060.00 | |||
Succinic semialdehyde, 50 mg | sc-397497C | 50 mg | $3787.00 |