Date published: 2026-4-1

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Succinic acid (CAS 110-15-6)

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Alternate Names:
Butanedioic acid
CAS Number:
110-15-6
Purity:
≥99%
Molecular Weight:
118.09
Molecular Formula:
C4H6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Succinic acid is a dicarboxylic acid. It plays a role in the citric acid cycle (Krebs cycle), a central pathway in cellular metabolism where it serves as an intermediate in the conversion of carbohydrates, fats, and proteins into carbon dioxide and water, thereby generating energy-rich ATP molecules. In research applications, succinic acid is often utilized as a precursor for the synthesis of polymers, resins, and solvents, owing to its reactivity and biodegradability. Its involvement in the citric acid cycle also makes it a critical compound for studies on metabolic processes and energy production in cells. Additionally, the chemical′s ability to donate and accept electrons makes it a valuable player in redox reactions, a property that is exploited in various biochemical and electrochemical studies. Succinic acid′s bifunctional nature, with two carboxylic acid functional groups, allows for its participation in cross-linking reactions, which is pivotal in the development of biodegradable polymers and as a building block in the manufacture of polyesters and alkyd resins. This versatility underscores its importance in the advancement of sustainable materials and energy research.


Succinic acid (CAS 110-15-6) References

  1. Continuous succinic acid fermentation by Actinobacillus succinogenes in a packed-bed biofilm reactor.  |  Ferone, M., et al. 2018. Biotechnol Biofuels. 11: 138. PMID: 29785205
  2. Genome shuffling improved acid-tolerance and succinic acid production of Actinobacillus succinogenes.  |  Hu, S., et al. 2019. Food Sci Biotechnol. 28: 817-822. PMID: 31093439
  3. Biochemical conversion of sweet sorghum bagasse to succinic acid.  |  Lo, E., et al. 2020. J Biosci Bioeng. 129: 104-109. PMID: 31400993
  4. Succinic acid production from whey and lactose by Actinobacillus succinogenes 130Z in batch fermentation.  |  Louasté, B. and Eloutassi, N. 2020. Biotechnol Rep (Amst). 27: e00481. PMID: 32518762
  5. Succinic acid inhibits the activity of cytochrome P450 (CYP450) enzymes.  |  Wang, H., et al. 2020. Pharm Biol. 58: 1150-1155. PMID: 33327821
  6. Novel biorefining method for succinic acid processed from sugarcane bagasse.  |  Chen, J., et al. 2021. Bioresour Technol. 324: 124615. PMID: 33454167
  7. Multiple inhibitory effects of succinic acid on Microcystis aeruginosa: morphology, metabolomics, and gene expression.  |  Chen, YD., et al. 2022. Environ Technol. 43: 3121-3130. PMID: 33843481
  8. Cocrystal formation of loratadine-succinic acid and its improved solubility.  |  Setyawan, D., et al. 2021. J Basic Clin Physiol Pharmacol. 32: 623-630. PMID: 34214360
  9. Fumaric acid and succinic acid treat gestational hypertension by downregulating the expression of KCNMB1 and TET1.  |  Zhou, Y., et al. 2021. Exp Ther Med. 22: 1072. PMID: 34447465
  10. The apoptotic efficacy of succinic acid on renal cancer cell lines.  |  Kasarci, G., et al. 2021. Med Oncol. 38: 144. PMID: 34687367
  11. Pharmacokinetic study on the interaction between succinic acid and irbesartan in rats and its potential mechanism.  |  Wang, Y., et al. 2021. Pharm Biol. 59: 1619-1622. PMID: 34818122
  12. Quantification of succinic acid levels, linked to succinate dehydrogenase (SDH) dysfunctions, by an automated and fully validated liquid chromatography tandem mass spectrometry method suitable for multi-matrix applications.  |  Lamy, C., et al. 2022. J Chromatogr B Analyt Technol Biomed Life Sci. 1189: 123085. PMID: 34974318
  13. Succinic acid exacerbates experimental autoimmune uveitis by stimulating neutrophil extracellular traps formation via SUCNR1 receptor.  |  Li, H., et al. 2022. Br J Ophthalmol.. PMID: 35346946
  14. Production of succinic acid through the fermentation of Actinobacillus succinogenes on the hydrolysate of Napier grass.  |  Lee, JS., et al. 2022. Biotechnol Biofuels Bioprod. 15: 9. PMID: 35418147
  15. Pharmacokinetics and Tissue Distribution of 13C-Labeled Succinic Acid in Mice.  |  Jung, Y., et al. 2022. Nutrients. 14: PMID: 36432443

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Succinic acid, 25 g

sc-212961B
25 g
$45.00

Succinic acid, 500 g

sc-212961
500 g
$75.00

Succinic acid, 1 kg

sc-212961A
1 kg
$133.00