Date published: 2025-12-24

1-800-457-3801

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Streptococcus Group A Antibody (3401): sc-58043

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Datasheets
  • Streptococcus Group A Antibody (3401) is a mouse monoclonal IgM provided at 100 µg/ml
  • raised against Streptococcus Group A whole cells fixed and digested to remove protein
  • recommended for detection of Streptococcus Group A by IP and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Streptococcus Group A Antibody (3401). This work is in progress.

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    Streptococcus Group A Antibody (3401) is a mouse monoclonal IgM antibody that detects Streptococcus Group A with non-specific reactivity across various species by immunoprecipitation (IP) and enzyme-linked immunosorbent assay (ELISA). Streptococcus Group A, a Gram-positive bacterium, is notorious for causing diseases ranging from mild pharyngitis to severe invasive infections like necrotizing fasciitis and streptococcal toxic shock syndrome. Streptococcus Group A monoclonal antibody (3401) recognizes group-specific polysaccharides that facilitate bacterial adherence to host tissues, crucial for colonization and subsequent infection. Group-specific polysaccharides are integral to bacterial virulence, enabling evasion of host immune response and establishment of infection. Understanding Streptococcus Group A interactions with host cells is vital for developing effective therapeutic strategies and improving clinical outcomes. Early recognition and treatment of Streptococcus Group A infections are essential, as untreated cases can lead to severe complications. Anti-Streptococcus Group A antibody (3401) serves as a valuable tool in research and diagnostic applications, aiding in pathogen detection and study.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Streptococcus Group A Antibody (3401) References:

    1. Epidemiology of streptococcus group A in school aged children in Pemba.  |  Braito, A., et al. 2004. East Afr Med J. 81: 307-12. PMID: 16167678
    2. Association between C-reactive protein rapid test and group A streptococcus infection in acute pharyngitis.  |  Calviño, O., et al. 2014. J Am Board Fam Med. 27: 424-6. PMID: 24808122
    3. Lethal infection by Streptococcus group A in thyroid surgery: the importance of an early diagnosis.  |  López-López, V., et al. 2018. Cir Esp (Engl Ed). 96: 385-387. PMID: 29129264
    4. Have reducing tonsillectomy rates in England led to increasing incidence of invasive Group A Streptococcus infections in children?  |  Banigo, A., et al. 2018. Clin Otolaryngol. 43: 912-919. PMID: 29505705
    5. Alterations in the Nervous System and Gut Microbiota after β-Hemolytic Streptococcus Group A Infection-Characteristics and Diagnostic Criteria of PANDAS Recognition.  |  Baj, J., et al. 2020. Int J Mol Sci. 21: PMID: 32098238
    6. State-of-the-art of invasive Group A Streptococcus infection in children: protocol for a scoping review of the literature with a focus on predictors of invasive infection.  |  Mariani, F., et al. 2023. F1000Res. 12: 209. PMID: 38778805
    7. Streptococcus group A injection for the treatment of lymphatic leakage after single-port robotic-assisted radical prostatectomy: A case report.  |  Yang, Z., et al. 2024. Asian J Surg. 47: 3719-3720. PMID: 38821824
    8. Group A Streptococcus Infections in Children: Epidemiological Insights Before and After the COVID-19 Pandemic.  |  Karapati, E., et al. 2024. Pathogens. 13: PMID: 39599560
    9. Transferred nuclear Overhauser enhancement experiments show that the monoclonal antibody strep 9 selects a local minimum conformation of a Streptococcus group A trisaccharide-hapten.  |  Weimar, T., et al. 1995. Biochemistry. 34: 13672-81. PMID: 7577958
    10. [Cellular constituents and extracellular proteins involved in the pathogenic capacity of Streptococcus group A].  |  Alouf, J. and Müller-Alouf, H. 1996. Ann Pharm Fr. 54: 49-59. PMID: 8734328

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Streptococcus Group A Antibody (3401)

    sc-58043
    100 µg/ml
    $316.00