STK19 Antibody (3B6): sc-100427

STK19 Antibody (3B6) is a mouse monoclonal IgG2a kappa light chain antibody that detects STK19 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-STK19 antibody (3B6) is available as the non-conjugated format. STK19, also known as serine/threonine kinase 19, G11, RP1, D6S60, D6S60E, or HLA-RP1, is a crucial 368 amino acid protein that plays a significant role in cellular signaling pathways by catalyzing the phosphorylation of serine and threonine residues on target proteins, including histones and caseins. This phosphorylation is vital for regulating various cellular processes such as cell division, differentiation, DNA repair, and transcription, making STK19 an important player in maintaining cellular homeostasis and responding to external stimuli. Located primarily in the nucleus, STK19 is expressed in various cell types, including monocytes, hepatocytes, epithelial cells, and T- and B-lymphocytes, and functions in an ATP-dependent manner, utilizing divalent cations like manganese as cofactors. Additionally, the existence of multiple isoforms of STK19 due to alternative splicing events adds complexity to its regulatory functions, highlighting its importance in diverse biological contexts.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

STK19 Antibody (3B6) References:

1. Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells.  |  Liu, F., et al. 2002. J Biol Chem. 277: 32099-108. PMID: 12050161
2. The rat expresses two complement factor C4 proteins, but only one isotype is expressed in the liver.  |  Roos, C., et al. 2005. J Immunol. 174: 970-5. PMID: 15634920
3. Characterization of Hap/BAG-1 variants as RP1 binding proteins with antiapoptotic activity.  |  Wadle, A., et al. 2005. Int J Cancer. 117: 896-904. PMID: 15986447
4. Characterisation of the novel gene G11 lying adjacent to the complement C4A gene in the human major histocompatibility complex.  |  Sargent, CA., et al. 1994. Hum Mol Genet. 3: 481-8. PMID: 8012361
5. Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region. Molecular cloning, exon-intron structure, composite retroposon, and breakpoint of gene duplication.  |  Shen, L., et al. 1994. J Biol Chem. 269: 8466-76. PMID: 8132574
6. The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinase.  |  Gomez-Escobar, N., et al. 1998. J Biol Chem. 273: 30954-60. PMID: 9812991

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-STK19 Antibody (3B6) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-STK19 Antibody (3B6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

STK19 Antibody (3B6) Specifications

Alternate Product Name: STK19

Product Clone Name: 3B6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 255-365

Epitope Target: STK19

Epitope Species: human

Product Reactivity/Detection: STK19

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for STK19 Antibody (3B6): N/A