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Stigmasterol acetate (CAS 4651-48-3)

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Alternate Names:
3β-Hydroxy-5,22-stigmastadiene 3-acetate; 5,22-Stigmastadien-3β-ol 3-acetate
CAS Number:
4651-48-3
Molecular Weight:
454.73
Molecular Formula:
C31H50O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Stigmasterol acetate, a plant sterol abundantly present in various plants and foods. This compound serves as a precursor for several hormones and vitamins. Stigmasterol acetate exhibits multiple mechanisms of action that contribute to its beneficial effects. One of its key actions involves modulating cholesterol metabolism, and it achieves this by acting as a ligand for the nuclear receptor LXRα, which plays a role in regulating cholesterol levels. By interacting with LXRα, stigmasterol acetate influences cholesterol metabolism, thereby potentially reducing cholesterol levels in the body. Furthermore, stigmasterol acetate displays anti-inflammatory properties by inhibiting the production of pro-inflammatory cytokines, the signaling molecules involved in the inflammatory response.


Stigmasterol acetate (CAS 4651-48-3) References

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  2. Stigmasterol, a soy lipid-derived phytosterol, is an antagonist of the bile acid nuclear receptor FXR.  |  Carter, BA., et al. 2007. Pediatr Res. 62: 301-6. PMID: 17622954
  3. Chemical Analysis of Surfaces by Use of Large-Angle Scattering of Heavy Charged Particles.  |  Turkevich, A. 1961. Science. 134: 672-4. PMID: 17731381
  4. Synthesis of highly pure oxyphytosterols and (oxy)phytosterol esters Part I. Regioselective hydrogenation of stigmasterol: an easy access to oxyphytosterols.  |  Geoffroy, P., et al. 2008. Steroids. 73: 702-7. PMID: 18387644
  5. [Study on steroidal and triterpenoid constituents from Cissus pteroclada].  |  Pan, GY., et al. 2013. Zhong Yao Cai. 36: 1274-7. PMID: 24558825
  6. Demonstration of biological activities of extracts from Isodon rugosus Wall. Ex Benth: Separation and identification of bioactive phytoconstituents by GC-MS analysis in the ethyl acetate extract.  |  Zeb, A., et al. 2017. BMC Complement Altern Med. 17: 284. PMID: 28558679
  7. Antinociceptive properties of steroids isolated from Phyllanthus corcovadensis in mice.  |  Santos, AR., et al. 1995. Planta Med. 61: 329-32. PMID: 7480179
  8. Fractionation of Soybean Oil Meal for Growth and Antiperotic Factors: 2. Studies with Genistin and Soysterols  |  P Vohra, JB Allred, IS Gupta, FH Kratzer - Poultry Science, 1959 - Elsevier. 1 November 1959,. Poultry Science. Volume 38, Issue 6,: Pages 1476-1477.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Stigmasterol acetate, 1 g

sc-296425
1 g
$133.00