Date published: 2026-2-2

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Stigmastanol (CAS 19466-47-8)

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Alternate Names:
Stigmastan-3-ol; Dihydro-β-sitosterol; Stigmastan-3β-ol
Application:
Stigmastanol is a plant lipid molecule that resembles cholesterol
CAS Number:
19466-47-8
Purity:
≥95%
Molecular Weight:
416.72
Molecular Formula:
C29H52O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Stigmastanol is a plant lipid molecule that resembles cholesterol in structure. Stigmasterol, a phytosterol present in various plant-based foods, has been utilized in the exploration of cholesterol metabolism mechanisms. It demonstrates the ability to inhibit the activity of HMG-CoA reductase, an essential enzyme involved in cholesterol synthesis.


Stigmastanol (CAS 19466-47-8) References

  1. An enzyme-linked immunosorbent assay for estrogenicity using primary hepatocyte cultures from the channel catfish (Ictalurus punctatus).  |  Monteverdi, GH. and Di Giulio, RT. 1999. Arch Environ Contam Toxicol. 37: 62-9. PMID: 10341043
  2. Cholesterol accumulation in tissues of the Niemann-pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ.  |  Xie, C., et al. 1999. Proc Natl Acad Sci U S A. 96: 11992-7. PMID: 10518564
  3. Disruption of the oxysterol 7alpha-hydroxylase gene in mice.  |  Li-Hawkins, J., et al. 2000. J Biol Chem. 275: 16536-42. PMID: 10748048
  4. Induction of bile acid synthesis by cholesterol and cholestyramine feeding is unimpaired in mice deficient in apolipoprotein AI.  |  Jolley, CD., et al. 2000. Hepatology. 32: 1309-16. PMID: 11093738
  5. Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration.  |  Xie, C., et al. 2003. J Lipid Res. 44: 1780-9. PMID: 12810827
  6. Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.  |  Davis, HR., et al. 2004. J Biol Chem. 279: 33586-92. PMID: 15173162
  7. Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae.  |  Backhouse, N., et al. 2008. J Ethnopharmacol. 116: 263-9. PMID: 18164566
  8. Protonated nanostructured aluminosilicate (NSAS) reduces plasma cholesterol concentrations and atherosclerotic lesions in Apolipoprotein E deficient mice fed a high cholesterol and high fat diet.  |  Sivak, O., et al. 2009. Lipids Health Dis. 8: 30. PMID: 19638223
  9. Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice.  |  Chi, L., et al. 2018. Molecules. 23: PMID: 29425148
  10. Dietary Supplementation of Black Rice Anthocyanin Extract Regulates Cholesterol Metabolism and Improves Gut Microbiota Dysbiosis in C57BL/6J Mice Fed a High-Fat and Cholesterol Diet.  |  Wang, H., et al. 2020. Mol Nutr Food Res. 64: e1900876. PMID: 32050056
  11. Multi-dimensional characterization and identification of sterols in untargeted LC-MS analysis using all ion fragmentation technology.  |  Qiu, J., et al. 2021. Anal Chim Acta. 1142: 108-117. PMID: 33280688
  12. Suppression on allergic airway inflammation of dehulled adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) in mice and anti-degranulation phytosterols from adlay bran.  |  Chung, CP., et al. 2021. Food Funct. 12: 12788-12799. PMID: 34854443
  13. Supercritical CO2 Extraction of Triterpenoids from Chaga Sterile Conk of Inonotus obliquus.  |  Huynh, N., et al. 2022. Molecules. 27: PMID: 35335249
  14. Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.  |  Schwarz, M., et al. 1997. J Biol Chem. 272: 23995-4001. PMID: 9295351

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Stigmastanol, 50 mg

sc-215913
50 mg
$316.00