Molecular structure of Ste11 MAPKKK Activation Inhibitor, CAS Number: 331662-51-2
Ste11 MAPKKK Activation Inhibitor (CAS 331662-51-2)
Alternate Names:
N-(2,4-dichlorophenyl)-6,7-dimethoxyquinazolin-4-amine
Application:
Ste11 MAPKKK Activation Inhibitor is reported to inhibit Ste 11 signalling and c-Abl Tyr kinase activity
CAS Number:
331662-51-2
Molecular Weight:
350.2
Molecular Formula:
C16H13Cl2N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Ste11 MAPKKK Activation Inhibitor is a quinazolinamine PD 153035 (sc-205909) analog that is reported to inhibit Ste11 signaling and c-Abl tyrosine kinase activity in yeast. Also reported to inhibit Src kinase activity with an IC50 of 250 nM.
Ste11 MAPKKK Activation Inhibitor (CAS 331662-51-2) References
- Synthesis and Src kinase inhibitory activity of a series of 4-phenylamino-3-quinolinecarbonitriles. | Boschelli, DH., et al. 2001. J Med Chem. 44: 822-33. PMID: 11262092
- Screening of drugs that suppress Ste11 MAPKKK activation in yeast identified a c-Abl tyrosine kinase inhibitor. | Kitagawa, T., et al. 2007. Biosci Biotechnol Biochem. 71: 772-82. PMID: 17341836
- Silencing PsKPP4, a MAP kinase kinase kinase gene, reduces pathogenicity of the stripe rust fungus. | Zhu, X., et al. 2018. Mol Plant Pathol. 19: 2590-2602. PMID: 30047240
Inhibitor of:
Tyrosine Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ste11 MAPKKK Activation Inhibitor, 5 mg | sc-355980 | 5 mg | $225.00 |