Stat6 Antibody (8C12): sc-81539
- Stat6 Antibody (8C12) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
- raised against a synthetic peptide corresponding to amino acids 650-670 of Stat6 of human origin
- recommended for detection of Stat6 of human and canine origin by WB, IP and IF
- See Stat6 (D-1): sc-374021 for Stat6 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Stat6 Antibody (8C12). This work is in progress.
Stat6 Antibody (8C12) is a mouse monoclonal IgG1 antibody that detects Stat6 in human and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Stat6 plays a crucial role in mediating the effects of interleukin-4 (IL-4) and interleukin-13 (IL-13), which are key cytokines involved in the immune response and regulation of inflammation. Upon activation by these cytokines, Stat6 undergoes phosphorylation, leading to dimerization and subsequent translocation to the nucleus, where Stat6 regulates the expression of genes associated with Th2 cell differentiation and allergic responses. The significance of Stat6 in these processes highlights potential therapeutic applications in conditions such as asthma and other allergic diseases. Anti-Stat6 antibody (8C12) provides reliable detection and characterization of Stat6, facilitating research into immune signaling pathways and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Stat6 Antibody (8C12) | sc-81539 | 50 µg/0.5 ml | $316.00 |