Stat6 Antibody (23): sc-136236
- Stat6 Antibody (23) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
- raised against amino acids 650-765 of Stat6 of human origin
- recommended for detection of Stat6 of mouse, rat and human origin by WB, IP and IF
- See Stat6 (D-1): sc-374021 for Stat6 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Stat6 Antibody (23). This work is in progress.
Stat6 Antibody (23) is a mouse monoclonal IgG1 antibody that detects Stat6 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Stat6 plays a crucial role in mediating the effects of interleukin-4 (IL-4) and interleukin-13 (IL-13), which are key cytokines involved in the immune response and regulation of allergic reactions. Upon activation by these cytokines, Stat6 undergoes phosphorylation, leading to dimerization and subsequent translocation to the nucleus, where Stat6 regulates the expression of genes associated with Th2 cell differentiation and IgE class switching. This function is particularly important in the context of asthma and other allergic diseases, as dysregulation of Stat6 signaling can contribute to the pathogenesis of these conditions. Anti-Stat6 antibody (23) provides reliable detection of Stat6, enabling researchers to explore Stat6′s role in various biological processes and disease states, thereby advancing our understanding of immune regulation and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Stat6 Antibody (23) | sc-136236 | 50 µg/0.5 ml | $322.00 |