Staphylococcus aureus TSST-1 Antibody (7917): sc-58197

Staphylococcus aureus TSST-1 Antibody (7917) is a mouse monoclonal IgG2a antibody that detects Staphylococcus aureus TSST-1 (TSST-1) with reactivity to human samples by enzyme-linked immunosorbent assay (ELISA). Staphylococcus aureus TSST-1 is a potent exotoxin that plays a critical role in the pathogenesis of Toxic Shock Syndrome (TSS) by inducing a massive immune response through non-specific binding of major histocompatibility complex class II molecules with T cell receptors, leading to polyclonal T cell activation. This mechanism can result in severe systemic effects, including high fever, hypotension, and multi-organ failure, highlighting the need for effective detection and monitoring of TSST-1 in clinical settings. Anti-TSST-1 antibody (7917) facilitates research and diagnostic applications, providing a reliable tool for studying TSST-1′s implications in various autoimmune and allergic diseases, as well as antagonistic effects on interleukin-4-induced immunoglobulin E synthesis.