Date published: 2026-4-25

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Stachydrine Hydrochloride (CAS 4136-37-2)

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Application:
Stachydrine Hydrochloride is a potentially useful alkaloid for activity screening and an anticancer agent in vitro
CAS Number:
4136-37-2
Purity:
98%
Molecular Weight:
179.64
Molecular Formula:
C7H13NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Stachydrine Hydrochloride is involved in the biosynthesis of choline and is a precursor to the neurotransmitter acetylcholine. Stachydrine Hydrochloride plays a role in osmoprotection and stress tolerance in plants, as it acts as a compatible solute and helps maintain cell turgor during periods of water deficit. Stachydrine Hydrochloride has antioxidant properties, scavenging free radicals and protecting cells from oxidative damage. Stachydrine Hydrochloride exhibits anti-inflammatory effects by modulating the production of pro-inflammatory cytokines. Stachydrine Hydrochloride can enhance the shelf life of certain products due to its ability to inhibit lipid oxidation.


Stachydrine Hydrochloride (CAS 4136-37-2) References

  1. Simultaneous determination of 10 active components in traditional Chinese medicine 'YIGONG' capsule by RP-HPLC-DAD.  |  Feng, C., et al. 2008. J Pharm Biomed Anal. 47: 442-7. PMID: 18314288
  2. The Th1/Th2/Th17/Treg paradigm induced by stachydrine hydrochloride reduces uterine bleeding in RU486-induced abortion mice.  |  Li, X., et al. 2013. J Ethnopharmacol. 145: 241-53. PMID: 23178269
  3. The influence of stachydrine hydrochloride on the reperfusion model of mice with repetitive cerebral ischemia.  |  Miao, M., et al. 2017. Saudi J Biol Sci. 24: 658-663. PMID: 28386193
  4. Stachydrine hydrochloride inhibits proliferation and induces apoptosis of breast cancer cells via inhibition of Akt and ERK pathways.  |  Wang, M., et al. 2017. Am J Transl Res. 9: 1834-1844. PMID: 28469788
  5. [Determination of stachydrine hydrochloride and leonurine hydrochloride in Yimucao preparations by HPLC-MS].  |  Zhou, C., et al. 2016. Zhongguo Zhong Yao Za Zhi. 41: 1876-1879. PMID: 28895336
  6. [Optimize concentrate process of alkaloid from Leonurus japonicus by ultrafultration-nanofiltration coupling technology].  |  Li, CY., et al. 2017. Zhongguo Zhong Yao Za Zhi. 42: 100-106. PMID: 28945032
  7. [Standard decoction of Leonuri Herba].  |  Deng, Z., et al. 2017. Zhongguo Zhong Yao Za Zhi. 42: 3523-3529. PMID: 29218937
  8. Effect of stachydrine hydrochloride to the prostate hyperplasia model in mice.  |  Tian, S., et al. 2019. Saudi J Biol Sci. 26: 782-789. PMID: 31049004
  9. Stachydrine hydrochloride alleviates pressure overload-induced heart failure and calcium mishandling on mice.  |  Chen, HH., et al. 2020. J Ethnopharmacol. 248: 112306. PMID: 31626909
  10. Stachydrine hydrochloride suppresses phenylephrine-induced pathological cardiac hypertrophy by inhibiting the calcineurin/nuclear factor of activated T-cell signalling pathway.  |  Zheng, J., et al. 2020. Eur J Pharmacol. 883: 173386. PMID: 32712088
  11. Stachydrine hydrochloride inhibits osteoclastogenesis by regulating the NF-κB and p38 signaling pathways to alleviate postmenopausal osteoporosis.  |  Chen, M., et al. 2021. Biochem Biophys Res Commun. 542: 1-8. PMID: 33482468
  12. Stachydrine hydrochloride inhibits hepatocellular carcinoma progression via LIF/AMPK axis.  |  Bao, X., et al. 2022. Phytomedicine. 100: 154066. PMID: 35366490
  13. Stachydrine hydrochloride ameliorates cardiac hypertrophy through CaMKII/HDAC4/MEF2C signal pathway.  |  Li, XQ., et al. 2022. Am J Transl Res. 14: 3840-3853. PMID: 35836883

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Stachydrine Hydrochloride, 10 mg

sc-296420
10 mg
$328.00