ss/ds DNA marker Antibody (5F151): sc-73063
- ss/ds DNA marker Antibody (5F151) is a mouse monoclonal IgM provided at 100 µg/ml
- raised against calf thymus DNA
- recommended for detection of single or double stranded eukaryotic DNA of mammalian origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ss/ds DNA marker Antibody (5F151). This work is in progress.
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ss/ds DNA marker Antibody (5F151) is a mouse monoclonal IgM antibody that detects deoxyribonucleic acid (DNA) in mammalian species through western blotting (WB). Anti-DNA antibody (5F151) plays a crucial role in distinguishing between double-stranded and single-stranded DNA, which is essential for understanding various biological processes, including DNA replication, repair, and transcription. DNA monoclonal antibody (5F151) enables differentiation between these two forms of DNA, as single-stranded DNA is often an intermediate during these processes, making DNA more susceptible to damage and mutations. Such specificity allows researchers to investigate DNA dynamics under different cellular conditions, providing insights into genetic stability and mechanisms of diseases such as cancer, where DNA damage is a significant factor. DNA (5F151) antibody effectively monitors DNA presence and state in samples, facilitating advancements in molecular biology and genetics research.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ss/ds DNA marker Antibody (5F151) References:
- A general solution for opening double-stranded DNA for isothermal amplification. | Chen, G., et al. 2016. Sci Rep. 6: 34582. PMID: 27687498
- Assessing Oligonucleotide Binding to Double-Stranded DNA. | Mozafari, N. and Umek, T. 2019. Methods Mol Biol. 2036: 91-112. PMID: 31410792
- Rapid in vitro production of single-stranded DNA. | Minev, D., et al. 2019. Nucleic Acids Res. 47: 11956-11962. PMID: 31713635
- Structural dynamics of double-stranded DNA with epigenome modification. | Furukawa, A., et al. 2021. Nucleic Acids Res. 49: 1152-1162. PMID: 33337470
- Single stranded DNA annealing is a conserved activity of telomere resolvases. | McGrath, SL., et al. 2021. PLoS One. 16: e0246212. PMID: 33539370
- Genome chromatinization in giant double-stranded DNA viruses. | Liu, Y. and Krupovic, M. 2022. Trends Biochem Sci. 47: 3-5. PMID: 34657789
- Conformation of ring single-stranded DNA measured by DNA origami structures. | Roth Weizman, E., et al. 2022. Biophys J. 121: 2127-2134. PMID: 35490298
- Correlation between double-stranded DNA and acute urticaria. | Li, Y., et al. 2024. Int J Dermatol. 63: e140-e147. PMID: 38385899
- Double-stranded DNA invasion by anti-gene oligonucleotide clamps. | De, A. and Bahal, R. 2024. Mol Ther Nucleic Acids. 35: 102385. PMID: 39650286
- Double-stranded DNA site-directed mutagenesis. | Viville, S. 1996. Methods Mol Biol. 57: 87-95. PMID: 8849997
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ss/ds DNA marker Antibody (5F151) | sc-73063 | 100 µg/ml | $322.00 |