ss/ds DNA marker Antibody (1.BB.27) is a mouse monoclonal IgG2b antibody that detects deoxyribonucleic acid (DNA) in mammalian species through western blotting (WB). ss/ds DNA marker (1.BB.27) antibody plays a crucial role in distinguishing between single-stranded and double-stranded DNA, which is essential for various molecular biology applications, including the study of DNA replication, repair, and transcription. The structure of DNA, characterized by its double helix formation, is vital for stability and function, as DNA allows for precise pairing of nucleotide bases—adenine with thymine and guanine with cytosine—ensuring accurate genetic information storage and transmission. ss/ds DNA marker (1.BB.27) monoclonal antibody binds specifically to these forms of DNA, enabling researchers to investigate DNA dynamics under different physiological and experimental conditions, providing insights into cellular processes and potential disease mechanisms. Anti-ss/ds DNA marker antibody (1.BB.27) enhances understanding of genetic regulation and molecular underpinnings of various biological phenomena.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ss/ds DNA marker Antibody (1.BB.27) References:
- TTV, a new human virus with single stranded circular DNA genome. | Hino, S. 2002. Rev Med Virol. 12: 151-8. PMID: 11987140
- Site-specific integration of Agrobacterium tumefaciens T-DNA via double-stranded intermediates. | Tzfira, T., et al. 2003. Plant Physiol. 133: 1011-23. PMID: 14551323
- Single-stranded DNA as an immunohistochemical marker of neuronal damage in human brain: an analysis of autopsy material with regard to the cause of death. | Michiue, T., et al. 2008. Forensic Sci Int. 178: 185-91. PMID: 18462896
- DNA single- and double-strand breaks by alkaline- and immuno-comet assay in lymphocytes of workers exposed to styrene. | Fracasso, ME., et al. 2009. Toxicol Lett. 185: 9-15. PMID: 19095051
- Quantitative analysis of single-stranded DNA immunoreactivity as a marker of neuronal apoptosis in hippocampus with regard to the causes of death in medicolegal autopsy. | Michiue, T., et al. 2009. Leg Med (Tokyo). 11 Suppl 1: S168-70. PMID: 19278886
- The deinococcal DdrB protein is involved in an early step of DNA double strand break repair and in plasmid transformation through its single-strand annealing activity. | Bouthier de la Tour, C., et al. 2011. DNA Repair (Amst). 10: 1223-31. PMID: 21968057
- Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques. | Sköld, AE., et al. 2012. Blood. 120: 768-77. PMID: 22700721
- Biotinylation of double stranded DNA after transamination. | Avignolo, C., et al. 1990. Biochem Biophys Res Commun. 170: 243-50. PMID: 2372289
- Nanopore-based assay for detection of methylation in double-stranded DNA fragments. | Shim, J., et al. 2015. ACS Nano. 9: 290-300. PMID: 25569824
- Pervasive Chimerism in the Replication-Associated Proteins of Uncultured Single-Stranded DNA Viruses. | Kazlauskas, D., et al. 2018. Viruses. 10: PMID: 29642587