SR 11302 (CAS 160162-42-5)
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Available in US only.
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SR 11302 is a compound often utilized in biochemical research, particularly in studies that focus on gene expression regulation. Its role as an AP-1 transcription factor inhibitor makes it useful in examining the pathways through which AP-1 regulates gene expression and influences cellular processes such as proliferation and differentiation. Research involving SR 11302 may explore its effects on signal transduction pathways that lead to AP-1 activation, providing insights into the molecular basis of various biological responses. Additionally, the compound is used to dissect the contributions of AP-1 in cellular responses to oxidative stress and its involvement in the regulation of inflammatory cytokines. By inhibiting AP-1 activity, SR 11302 aids researchers in determining the downstream effects of this transcription factor and how it may interact with other signaling molecules within the cell.
SR 11302 (CAS 160162-42-5) References
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- AP-1 Inhibition by SR 11302 Protects Human Hepatoma HepG2 Cells from Bile Acid-Induced Cytotoxicity by Restoring the NOS-3 Expression. | González-Rubio, S., et al. 2016. PLoS One. 11: e0160525. PMID: 27490694
- SR 11302, an AP-1 Inhibitor, Reduces Metastatic Lesion Formation in Ex Vivo 4D Lung Cancer Model. | Mishra, DK. and Kim, MP. 2017. Cancer Microenviron. 10: 95-103. PMID: 29177791
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SR 11302, 10 mg | sc-204295 | 10 mg | $357.00 | |||
| US: Only available in the US | ||||||