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Sphingomyelinase (Staphylococcus aureus) (CAS 9031-54-3)

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Alternate Names:
Sphingomyelin cholinephosphohydrolase
CAS Number:
9031-54-3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sphingomyelinase (Staphylococcus aureus) is an enzyme that catalyzes the hydrolysis of sphingomyelin to produce phosphorylcholine and ceramide. This enzyme plays a role in disrupting the host cell membrane by cleaving sphingomyelin, which is a major component of the lipid rafts in the plasma membrane. By targeting and hydrolyzing sphingomyelin, this enzyme can disrupt the integrity of the host cell membrane, potentially facilitating the entry of the bacterium into the host cell. This mechanism of action allows the bacterium to evade the host immune response and establish infection. The production of ceramide as a result of sphingomyelinase activity may also contribute to the pathogenesis of Staphylococcus aureus by affecting host cell signaling pathways. Sphingomyelinase (Staphylococcus aureus) plays a role in the pathogenicity of the bacterium by disrupting host cell membranes and modulating host cell signaling.


Sphingomyelinase (Staphylococcus aureus) (CAS 9031-54-3) References

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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sphingomyelinase (Staphylococcus aureus), 10 U

sc-471277
10 U
$103.00