Spermine, Tetrahydrochloride (CAS 306-67-2)

Spermine, Tetrahydrochloride (STHC) is a biogenic polyamine that occurs naturally in almost all tissues, derived from spermidine (sc-215900). Widely utilized in scientific research, Spermine, Tetrahydrochloride is an organic compound with a range of biological activities. It plays a role in neoplastic and normal tissue growth and modulates calcium-dependent immune processes. Although the exact mechanism of action is not fully understood, Spermine, Tetrahydrochloride is believed to bind to specific cell surface receptors, activating various intracellular signaling pathways that regulate diverse cellular processes. Spermine, Tetrahydrochloride exhibits multiple effects, including the inhibition of NOS1 (nNOS), activation or inhibition of NMDA depending on receptor subunit composition, inhibition of GluR, and activation of PLCα and PLCδ. Researchers have conducted studies to assess the impact of Spermine, Tetrahydrochloride on various biological processes, unveiling its anti-inflammatory, antioxidant, and antifungal properties. Furthermore, Spermine, Tetrahydrochloride has demonstrated potential in reducing the risk of certain cancers. Animal models and cell cultures have been employed to investigate the effects of drugs on the body, utilizing Spermine, Tetrahydrochloride as an important component in these studies.