Spermidine trihydrochloride (CAS 334-50-9)

Spermidine trihydrochloride, a stable hydrochloride salt form of spermidine, plays a pivotal role in cellular processes through its involvement in polyamine biosynthesis and regulation. As a naturally occurring polyamine, it is primarily engaged in the modulation of ribonucleic acid (RNA) interactions, stabilization of nucleic acid structures, and promotion of enzyme activities for cell growth and viability. Its mechanism of action is intricately linked to autophagy, a fundamental cellular process responsible for the degradation and recycling of cellular components. This process is essential for cellular homeostasis, differentiation, development, and survival under stress conditions. In research, spermidine trihydrochloride is extensively utilized as a tool to study autophagy pathways and mechanisms, enabling the exploration of cellular responses to various stressors and the elucidation of the complex interplay between autophagy and other cellular processes. Through these studies, spermidine trihydrochloride serves as a key compound in unraveling the molecular underpinnings of cell biology, offering insights into the mechanisms that govern cellular maintenance and longevity.